Protein Alignment Fas1 and Fas1

DIOPT Version :10

• Sequence 1: NP_001097814.1
• Gene: Fas1 / 42025
• FlyBaseID: FBgn0285925
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_061508408.1
• Gene: Fas1 / 1270463
• VectorBaseID: AGAMI1_010052
• Length: 680
• Species: Anopheles gambiae
• Alignment Length: 675
• Identity: 276/675 - (40%)
• Similarity: 414/675 - (61%)
• Gaps: 41/675 - (6%)

  Fly     2 LNAAALLLALLCAANAAAAADLADKLRDDSELSQSTAKSLRRLMPVRFYSLLESNQIANSTLSLR 66
            |.|...||..:.....:::..|..::|||.:||:             ||||:|.::||.|.|...
Mosquito    21 LLACLQLLPTVWTVGRSSSVTLEARMRDDPDLSE-------------FYSLIERDEIAMSRLVHH 72

  Fly    67 SCTIFVPTNEAFQRYKSKTAHVLYHITTEAYTQKRLPNTVSSDMAGNPPLYITK-----NSNGDI 126
            ..|||.|||:|||.|.:...|:.||:::......:|.:||.|......|||||:     ....|:
Mosquito    73 PLTIFAPTNQAFQSYLNNKTHLNYHMSSTPLRLSQLGDTVRSLNDDGTPLYITRRRPLSGMQEDL 137

  Fly   127 FVNNARIIPSLS-VE-TNSDGKRQIMHIIDEVLEPLTVKAGHS-DTPNNPNALKFLKNAEEFNVD 188
            :||:|:|:...| :| .|:.|..||:||||:||.|:|.....: ||| ||:|..||::.|..|::
Mosquito   138 YVNSAKIVRERSNMEFKNTRGYTQILHIIDDVLTPITTVFNKTLDTP-NPDAWGFLQSVEAINIE 201

  Fly   189 NIGVRTYRSQVTMAKKESVYDAAGQHTFLVPVDEGFKL--SARSSLVDGKVIDGHVIPNTVIFTA 251
            ...||::|.::...|::.|:..:|..||.:||:.|||:  :...|::|.:|||||||||..|||.
Mosquito   202 PHRVRSFRKKILNLKRDQVFKKSGISTFFIPVETGFKVPPNPTLSMIDKRVIDGHVIPNKAIFTT 266

  Fly   252 AAQHDDPKASAAFEDLLKVTVSFFKQKNGK----MYVKSNTIVGDAKHRVGVVLAEIVKANIPVS 312
            .|.:..|..:..|||.|:||::||:.:.||    ::|.|||:..:::...|.|:|||||.||||:
Mosquito   267 PAPYGKPLETLQFEDDLRVTITFFRHETGKNTHRVFVVSNTMYSNSRLTPGAVIAEIVKPNIPVA 331

  Fly   313 NGVVHLIHRPLMIIDTTVTQFLQENAENGALRKFYEVIMDNGGAVLDDINSLTEVTILAPSNEAW 377
            |||||||||||:|:|....|.|.:|:.. ...||.::|.|.....|:.:..::::|:..|.:||.
Mosquito   332 NGVVHLIHRPLVIVDMHGMQMLTDNSHT-LWSKFRDLIEDYAPEFLNVLRGMSQMTLFVPQDEAV 395

  Fly   378 NSSNINNVLRDRNKMRQILNMHIIKDRLNVDKIRQKNANLIAQVPTVNNNTFLYFNVRGEGS--D 440
            ......|.:.:|.|:.::|.||::.|.:.:|||::.|.|.|.|:||:|:..|||||:....:  |
Mosquito   396 AQMMQTNFMSNRKKLLEVLMMHVVPDAITIDKIKRNNQNHIYQIPTMNSRRFLYFNLNENRTTHD 460

  Fly   441 TVITVEGGGVNATVIQADVAQTNGYVHIIDHVLGVPYTTVLGKLESDPMMSDTYKMGKFSHFNDQ 505
            ..:|||||||||:::..|:|..:||:||||.:|||.|.||..|||:|||::.||..||.:|||||
Mosquito   461 KSVTVEGGGVNASLVLGDIATKDGYIHIIDRMLGVSYMTVQEKLETDPMLNLTYHFGKLNHFNDQ 525

  Fly   506 LNNTQRRFTYFVPRDKGWQKTELDYPSAHKKLFMADFSYHSKSILERHLAISDKEYTMKDLVKFS 570
            ||.|.:||||||||||.|.:..:::|:|:...|:.: ...|:.:||.||.::|:.::|.||...|
Mosquito   526 LNMTNKRFTYFVPRDKAWIQWFIEHPAANLDDFVRN-REQSRMVLEHHLIVADRVFSMGDLRNMS 589

  Fly   571 QESGSVILPTF-RDSLSIRVEEEAGRYVIIWNY--KKINVYRPDVECTNGIIHVIDYPLLEEKDV 632
            .:  |:||||. .:||.|||:||..||.|.|..  :...|:|.|||||||:|||||.|.:.|.|:
Mosquito   590 HD--SLILPTVGLESLQIRVKEEDNRYFIQWKETGRWTTVFRADVECTNGLIHVIDVPFVHEYDM 652

  Fly   633 VVAGGSYLPESSICIILANLIMITV 657
            :.:.|..|    ..|....|:::||
Mosquito   653 ITSDGHRL----YGIEPLTLLLVTV 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fas1	NP_001097814.1	Fasciclin	49..159	CDD:396845	48/116 (41%)
		FAS1	215..324	CDD:214719	58/114 (51%)
		FAS1	368..476	CDD:214719	46/109 (42%)
		Fasciclin	488..627	CDD:396845	69/141 (49%)
Fas1	XP_061508408.1	None