DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14893 and FAR6

DIOPT Version :9

Sequence 1:	NP_650568.2	Gene:	CG14893 / 42023	FlyBaseID:	FBgn0038451	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001326776.1	Gene:	FAR6 / 824837	AraportID:	AT3G56700	Length:	548	Species:	Arabidopsis thaliana

Alignment Length:	519	Identity:	136/519 - (26%)
Similarity:	220/519 - (42%)	Gaps:	120/519 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTPNNIVSRTEMDNGIQGFYKDKVVFLTGATGFLGKVIIEKLLR-TTEVKRIYAMMRPKRGKDIQ 64
            :||....||.....||..|.:.|...:|||||||.||:|||||| :.|:.:|:.:||.|..:...
plant    62 VTPKTETSRNSDGIGIVRFLEGKSYLVTGATGFLAKVLIEKLLRESLEIGKIFLLMRSKDQESAN 126

  Fly    65 ERL--AIWQKDPLFEVLLKAKPDAL-----KRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHG 122
            :||  .|...| ||::|.:....:.     :::..:.||..:.:|||......::..|:.::|..
plant   127 KRLYDEIISSD-LFKLLKQMHGSSYEAFMKRKLIPVIGDIEEDNLGIKSEIANMISEEIDVIISC 190

  Fly   123 AATVRFNEPLHVALAINTRGTRLMLQLAKEMLQLEAYLHISTAFSN------------CVIFRIE 175
            .....|::....||::|..|...:|...|...:|:.:||.|||:..            |:
plant   191 GGRTTFDDRYDSALSVNALGPGRLLSFGKGCRKLKLFLHFSTAYVTGKREGTVLETPLCI----- 250

  Fly   176 EKFYPEHLTCDANSVLAMSELLSEQMMDKLAPTLVGNF----------------------PNTYT 218
                .|::|.|.|   ..|||       |||...|..|                      .|:||
plant   251 ----GENITSDLN---IKSEL-------KLASEAVRKFRGREEIKKLKELGFERAQHYGWENSYT 301

  Fly   219 YTKALAEDVVLREFGDLPLSIFRPSVIIATHEEPVSGWID--NLYGPIAHIYGVSHGVLRLTTYD 281
            :|||:.|.|:..:.|:||:.|.|||:|.:::.||..|||.  .:..||  |...:.|.:.....|
plant   302 FTKAIGEAVIHSKRGNLPVVIIRPSIIESSYNEPFPGWIQGTRMADPI--ILAYAKGQISDFWAD 364

  Fly   282 KDGYASLVPVDYCANAALASIWQTSKDKSQRNAISQP--AIYTL-APSEKNLLLNTDFIKHSLIH 343
            ......::|||..||||:|::        .::....|  .:|.| :.|..|.:.....|..|..|
plant   365 PQSLMDIIPVDMVANAAIAAM--------AKHGCGVPEFKVYNLTSSSHVNPMRAGKLIDLSHQH 421

  Fly   344 RNDFPLTKMIWYPFVHNISNPRIFPLAAFFYHTLPGYFYDLA----------------LRLSGRK 392
            ..||||.:.     |.::.:.:|       :.:|.|:...|:                |...|::
plant   422 LCDFPLEET-----VIDLEHMKI-------HSSLEGFTSALSNTIIKQERVIDNEGGGLSTKGKR 474

  Fly   393 P-----RLVKLYRSIHANIAVLEHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDWKEY 451
            .     .|.|.|          |.:......|:..:|..|...||.|:::.:.||::.:||:.|
plant   475 KLNYFVSLAKTY----------EPYTFFQARFDNTNTTSLIQEMSMEEKKTFGFDIKGIDWEHY 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14893	NP_650568.2	PLN02996	19..452	CDD:215538	130/501 (26%)
		FAR-N_SDR_e	23..339	CDD:187547	101/362 (28%)
		Sterile	375..465	CDD:281068	20/98 (20%)
FAR6	NP_001326776.1	PLN02996	77..539	CDD:215538	131/504 (26%)
		FAR-N_SDR_e	84..426	CDD:187547	104/371 (28%)
		FAR_C	<471..539	CDD:176924	16/68 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.970