DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14893 and MS2

DIOPT Version :9

Sequence 1:	NP_650568.2	Gene:	CG14893 / 42023	FlyBaseID:	FBgn0038451	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_187805.1	Gene:	MS2 / 820372	AraportID:	AT3G11980	Length:	616	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	136/512 - (26%)
Similarity:	230/512 - (44%)	Gaps:	82/512 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GIQGFYKDKVVFLTGATGFLGKVIIEKLLR-TTEVKRIYAMMRPKRGKDIQERLAIWQKD-PLFE 77
            ||..|.:.|...:||:||||.||:|||:|| ..:|.:||.:::.|..:...|||.....| .||.
plant   123 GIISFLQGKKFLITGSTGFLAKVLIEKVLRMAPDVSKIYLLIKAKSKEAAIERLKNEVLDAELFN 187

  Fly    78 VLLKAKPDA-----LKRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHGAATVRFNEPLHVALA 137
            .|.:....:     |.::..:.|:..|.::|:.....:.:..||.::|:.||...|||...|||.
plant   188 TLKETHGASYMSFMLTKLIPVTGNICDSNIGLQADSAEEIAKEVDVIINSAANTTFNERYDVALD 252

  Fly   138 INTRGTRLMLQLAKEMLQLEAYLHISTAFSN----------------CVIFRIEEKFYP---EHL 183
            |||||...::..||:..:|:.:|.:|||:.|                |:   ..|.|..   :.|
plant   253 INTRGPGNLMGFAKKCKKLKLFLQVSTAYVNGQRQGRIMEKPFSMGDCI---ATENFLEGNRKAL 314

  Fly   184 TCDANSVLAM--------SELLSEQMMD-KLAPTLVGNFPNTYTYTKALAEDVVLREFGDLPLSI 239
            ..|....||:        ::..:::|.| .|.......:.:||.:|||:.|.::....||:|:.|
plant   315 DVDREMKLALEAARKGTQNQDEAQKMKDLGLERARSYGWQDTYVFTKAMGEMMINSTRGDVPVVI 379

  Fly   240 FRPSVIIATHEEPVSGWID--NLYGPIAHIYGVSHGVLRLTTYDKDGYASLVPVDYCANAALASI 302
            .|||||.:|:::|..||::  .:..||...||  .|.|.....|..|...:||.|...||.||:|
plant   380 IRPSVIESTYKDPFPGWMEGNRMMDPIVLCYG--KGQLTGFLVDPKGVLDVVPADMVVNATLAAI 442

  Fly   303 WQTSKDKSQRNAISQPA----IYTLAPSEKNLLLNTDFIKHSLIHRNDFPLTKMIWYPFVHNISN 363
                  .....|:|.|.    :|.:|.|..|.|:..|..:  |:: |.:..:     |.:.:..:
plant   443 ------AKHGMAMSDPEPEINVYQIASSAINPLVFEDLAE--LLY-NHYKTS-----PCMDSKGD 493

  Fly   364 PRIFPLAAFFYHTLPGYFYDLALRLSGRKPRLVKLYRSIHANI-------------------AVL 409
            |.:..|...|...  ..|.|...|.:..:..|:....|:.:.:                   .:.
plant   494 PIMVRLMKLFNSV--DDFSDHLWRDAQERSGLMSGMSSVDSKMMQKLKFICKKSVEQAKHLATIY 556

  Fly   410 EHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDWKEYFRKA-LFGMRLYLTK 465
            |.:......|:..:|.||...||.:::|.:.||:.:::|.:|.... :.|:|.::.|
plant   557 EPYTFYGGRFDNSNTQRLMENMSEDEKREFGFDVGSINWTDYITNVHIPGLRRHVLK 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14893	NP_650568.2	PLN02996	19..452	CDD:215538	130/492 (26%)
		FAR-N_SDR_e	23..339	CDD:187547	107/356 (30%)
		Sterile	375..465	CDD:281068	19/109 (17%)
MS2	NP_187805.1	PLN02503	1..616	CDD:215279	136/512 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.970