Protein Alignment CG14893 and Far1

DIOPT Version :10

• Sequence 1: NP_650568.2
• Gene: CG14893 / 42023
• FlyBaseID: FBgn0038451
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_081655.2
• Gene: Far1 / 67420
• MGIID: 1914670
• Length: 515
• Species: Mus musculus
• Alignment Length: 498
• Identity: 170/498 - (34%)
• Similarity: 268/498 - (53%)
• Gaps: 21/498 - (4%)

  Fly    16 IQGFYKDKVVFLTGATGFLGKVIIEKLLRT-TEVKRIYAMMRPKRGKDIQERLAIWQKDPLFEVL 79
            |..:|:.|.:.|||||||||||::|||||: ..|..:|.::|.|.|:..|||:.......||:.|
Mouse     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSKLFDRL 68

  Fly    80 LKAKPDALKRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHGAATVRFNEPLHVALAINTRGTR 144
            ....||..::|..|..:...|.|.::..|:::::...:::.|.||||||||.|..|:.:|...||
Mouse    69 RDENPDFREKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   145 LMLQLAKEMLQLEAYLHISTAFSNCVIFRIEEKFYPEHLTCDANSVLAMSELLSEQMMDKLAPTL 209
            .::.||::|..||.::|:|||::.|....|:|..||..:  |...::...|.:.:.:::.:.|.|
Mouse   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPV--DPKKLIDSLEWMDDGLVNDITPKL 196

  Fly   210 VGNFPNTYTYTKALAEDVVLREFGDLPLSIFRPSVIIATHEEPVSGWIDNLYGPIAHIYGVSHGV 274
            :|:.||||.|||||||.||.:|...|.::|.|||::.|:.:||..|||||..||.........|:
Mouse   197 IGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   275 LRLTTYDKDGYASLVPVDYCANAALASIWQTSKDKSQRNAISQPAIYTLAPSEKNLLLNTDFIKH 339
            ||......:..|.|||||...|.:||:.|.:..:: .||.:    :|.......|.....:...|
Mouse   262 LRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNR-PRNIM----VYNCTTGSTNPFHWGEVEYH 321

  Fly   340 --SLIHRNDFPLTKMIWYPFVHNISNPRIFPLAAFFYHTLPGYFYDLALRLSGRKPRLVKLYRSI 402
              |...||  ||.:....|.|:..||..::.......|..|.:.||:.||::||.||::|....:
Mouse   322 VISTFKRN--PLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPRMMKTITRL 384

  Fly   403 HANIAVLEHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDWKEYFRKALFGMRLYLTKEP 467
            |..:..||:|.:|||.:.|.:.:.|...::|||::.:|.|:..|.|.||......|.:.|:..|
Mouse   385 HKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVLNE- 448

  Fly   468 PTQESLEQGRRLFYRLKILHYSFVTLLCVIAGFLLWTLVRLFI 510
             ....|...|:...:|:.:.|.|.|:|.:    |:|   |:||
Mouse   449 -EMSGLPAARKHLNKLRNIRYGFNTILVI----LIW---RIFI 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14893	NP_650568.2	FAR-N_SDR_e	23..339	CDD:187547	114/316 (36%)
		Sterile	374..465	CDD:460779	31/90 (34%)
Far1	NP_081655.2	FAR-N_SDR_e	11..330	CDD:187547	118/327 (36%)
		Sterile	357..447	CDD:460779	31/89 (35%)
		Necessary and sufficient for PEX19-mediated localization into peroxisome membrane. /evidence=ECO:0000250|UniProtKB:Q8WVX9	451..507		12/40 (30%)