DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14893 and Far1

DIOPT Version :9

Sequence 1:	NP_650568.2	Gene:	CG14893 / 42023	FlyBaseID:	FBgn0038451	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001272760.1	Gene:	Far1 / 67420	MGIID:	1914670	Length:	515	Species:	Mus musculus

Alignment Length:	499	Identity:	171/499 - (34%)
Similarity:	270/499 - (54%)	Gaps:	23/499 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IQGFYKDKVVFLTGATGFLGKVIIEKLLRT-TEVKRIYAMMRPKRGKDIQERLAIWQKDPLFEVL 79
            |..:|:.|.:.|||||||||||::|||||: ..|..:|.::|.|.|:..|||:.......||:.|
Mouse     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSKLFDRL 68

  Fly    80 LKAKPDALKRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHGAATVRFNEPLHVALAINTRGTR 144
            ....||..::|..|..:...|.|.::..|:::::...:::.|.||||||||.|..|:.:|...||
Mouse    69 RDENPDFREKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   145 LMLQLAKEMLQLEAYLHISTAFSNCVIFRIEEKFYPEHLTCDANSVLAMSELLSEQMMDKLAPTL 209
            .::.||::|..||.::|:|||::.|....|:|..||..:  |...::...|.:.:.:::.:.|.|
Mouse   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPV--DPKKLIDSLEWMDDGLVNDITPKL 196

  Fly   210 VGNFPNTYTYTKALAEDVVLREFGDLPLSIFRPSVIIATHEEPVSGWIDNLYGPIAHIYGVSHGV 274
            :|:.||||.|||||||.||.:|...|.::|.|||::.|:.:||..|||||..||.........|:
Mouse   197 IGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   275 LRLTTYDKDGYASLVPVDYCANAALASIWQTSKDKSQRNAISQPAIYTLAPSEKNLL---LNTDF 336
            ||......:..|.|||||...|.:||:.|.:..:: .||.:    :|.......|..   ...|:
Mouse   262 LRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNR-PRNIM----VYNCTTGSTNPFHWGEVGDY 321

  Fly   337 IKHSLIHRNDFPLTKMIWYPFVHNISNPRIFPLAAFFYHTLPGYFYDLALRLSGRKPRLVKLYRS 401
            :.||....   ||.::..:|:|...||..:........||:|....||||||:|:||.::|....
Mouse   322 LNHSFKMN---PLNQVFRHPYVKFCSNNLMLHYWKGVKHTVPALLLDLALRLTGQKPWMMKTITR 383

  Fly   402 IHANIAVLEHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDWKEYFRKALFGMRLYLTKE 466
            :|..:..||:|.:|||.:.|.:.:.|...::|||::.:|.|:..|.|.||......|.:.|:..|
Mouse   384 LHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVLNE 448

  Fly   467 PPTQESLEQGRRLFYRLKILHYSFVTLLCVIAGFLLWTLVRLFI 510
              ....|...|:...:|:.:.|.|.|:|.:    |:|   |:||
Mouse   449 --EMSGLPAARKHLNKLRNIRYGFNTILVI----LIW---RIFI 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14893	NP_650568.2	PLN02996	19..452	CDD:215538	154/436 (35%)
		FAR-N_SDR_e	23..339	CDD:187547	115/319 (36%)
		Sterile	375..465	CDD:281068	33/89 (37%)
Far1	NP_001272760.1	FAR-N_SDR_e	11..330	CDD:187547	117/328 (36%)
Far1	NP_001272760.1	Sterile	371..447	CDD:376978	24/75 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847911
Domainoid	1	1.000	96	1.000	Domainoid score	I7295
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750