DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14893 and FarO

DIOPT Version :9

Sequence 1:	NP_650568.2	Gene:	CG14893 / 42023	FlyBaseID:	FBgn0038451	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_652021.1	Gene:	FarO / 45707	FlyBaseID:	FBgn0023550	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	526	Identity:	147/526 - (27%)
Similarity:	246/526 - (46%)	Gaps:	77/526 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IQGFYKDKVVFLTGATGFLGKVIIEKLLRTTEVKRIYAMMRPKRGKDIQERLAIWQKDPLFEVLL 80
            ::.|::|..:|:||.:|.:||.::|||||:..|:|||.::||::....::||...::..:|.||.
  Fly     9 MEEFFEDSEIFVTGGSGVVGKALVEKLLRSCNVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVLA 73

  Fly    81 KAKPDALKRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHGAATVRFNEPLHVALAINTRGTRL 145
            ..||:.|.:|..:.||...|.|||:.|..:.: ..|.:|.|.||||||:|||..|:.:|..||..
  Fly    74 VQKPEELDKIVAVPGDVSLPGLGIDPSMMQRM-KGVSLVYHCAATVRFDEPLREAVRLNVGGTLE 137

  Fly   146 MLQLAKEMLQLEAYLHISTAFSNCVIFRIEEKFYPEHLTCDANSVLAM-SELLSEQMMDKLAPTL 209
            .|:.|:.:.||.|::|:||.:||..:.|:|.|:|...:  |....|.| .::..:.|::.|...|
  Fly   138 ALKFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPM--DWRLCLRMIDDVADDGMLNALTRKL 200

  Fly   210 VGNFPNTYTYTKALAEDVVLREFGDLPLSIFRPSVIIATHEEPVSGWIDNLYGPIAHIYGVSHGV 274
            :..||||||:||.|||.:|......||:.::|||:::...|:|..|:..:|.|.:.....|..|:
  Fly   201 IMGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVGAGI 265

  Fly   275 LRLTTYDKDGYASLVPVDYCANAALASIWQTSKDKSQRNAISQPAIYTL---------APSEKNL 330
            |:.....||....:.|.|.                    .|.....||.         .|::..:
  Fly   266 LKTVYLGKDIRLDITPQDI--------------------GIKSMLCYTKMGYDIYRQGPPADLPV 310

  Fly   331 LLNTD--FIKHSLIH----------RNDFPLTKMIWYPFVHNISNPRIFPLAAFFYHTLPGYFYD 383
            .|::.  .:.|:...          ..|....|.:..|..|.......:....|....||....|
  Fly   311 FLSSSCTHVPHTFTQIAEQMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILD 375

  Fly   384 LALRLSGRKPRLVKLYRSIHANIAVLEHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDW 448
            |.||:.|:||.|:...|..:..:.|::.||.|:|  ::.....:..:....:...:|||.
  Fly   376 LLLRIFGQKPVLMSAVRKAYQTLEVMQPFMFNNW--DSPGVSDMETLSKHGEGSAFNFDA----- 433

  Fly   449 KEYFR-------------KALFGMRLYLTKEPPTQESLEQGRRLFYRLKILHYSFVTLLCVIAGF 500
               |.             ..|..:|.:|.:|.|  ::||:.:|:. |:|:..|..:.|      |
  Fly   434 ---FNHPDIHGLVIQSCSNMLHSIRTHLLREDP--KTLERSKRIL-RIKVFLYRLLRL------F 486

  Fly   501 LLWTLV 506
            ||:.|:
  Fly   487 LLYKLI 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14893	NP_650568.2	PLN02996	19..452	CDD:215538	130/454 (29%)
		FAR-N_SDR_e	23..339	CDD:187547	103/327 (31%)
		Sterile	375..465	CDD:281068	23/102 (23%)
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	104/332 (31%)
FarO	NP_652021.1	FAR_C	379..>410	CDD:296071	11/32 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466750
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26995
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	10	9.860