DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14893 and CG17560

DIOPT Version :9

Sequence 1:	NP_650568.2	Gene:	CG14893 / 42023	FlyBaseID:	FBgn0038451	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_650567.1	Gene:	CG17560 / 42022	FlyBaseID:	FBgn0038450	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	499	Identity:	300/499 - (60%)
Similarity:	395/499 - (79%)	Gaps:	0/499 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 MDNGIQGFYKDKVVFLTGATGFLGKVIIEKLLRTTEVKRIYAMMRPKRGKDIQERLAIWQKDPLF 76
            ||:.||||:|:|.|||||.||||||||||||||||||.|||:::|||||..|::|:..|.|||:|
  Fly     1 MDSEIQGFFKNKTVFLTGGTGFLGKVIIEKLLRTTEVNRIYSLIRPKRGVPIEDRITTWAKDPVF 65

  Fly    77 EVLLKAKPDALKRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHGAATVRFNEPLHVALAINTR 141
            ||||:.|||||:|:..||||||||||||::||:::|.:||.|||||||||||:|.||::||||.|
  Fly    66 EVLLRTKPDALQRVCPIAGDCLDPDLGISQSDQRILTAEVQIVIHGAATVRFDEALHISLAINVR 130

  Fly   142 GTRLMLQLAKEMLQLEAYLHISTAFSNCVIFRIEEKFYPEHLTCDANSVLAMSELLSEQMMDKLA 206
            .|||||||||:|.||.:::|:|||:||||:..|.|:||||||.|.::.:||:.||:|.:::|.:.
  Fly   131 ATRLMLQLAKQMTQLVSFVHVSTAYSNCVVHDIAERFYPEHLNCSSDKILAVGELVSNKLLDAME 195

  Fly   207 PTLVGNFPNTYTYTKALAEDVVLREFGDLPLSIFRPSVIIATHEEPVSGWIDNLYGPIAHIYGVS 271
            |:|||:|||||||||||||||:|||.|:||||||||::|::|::||:.||:|||:||:|..:|.:
  Fly   196 PSLVGSFPNTYTYTKALAEDVILREAGNLPLSIFRPAIIMSTYKEPLVGWVDNLFGPLALCFGGA 260

  Fly   272 HGVLRLTTYDKDGYASLVPVDYCANAALASIWQTSKDKSQRNAISQPAIYTLAPSEKNLLLNTDF 336
            .|::|:||.|.....||||.|||.|.|||..|:|::...|...::.|.||..||||.||:...:|
  Fly   261 RGIMRVTTVDPSAKISLVPADYCVNVALACAWRTAEISVQNGKVTTPPIYAFAPSENNLMSYGNF 325

  Fly   337 IKHSLIHRNDFPLTKMIWYPFVHNISNPRIFPLAAFFYHTLPGYFYDLALRLSGRKPRLVKLYRS 401
            ||.|:|:|:..|||||:|||||..||...:|||||||.|||||||:||.|||.||||.||.|||.
  Fly   326 IKSSIIYRDIIPLTKMLWYPFVLCISTTSLFPLAAFFLHTLPGYFFDLLLRLKGRKPILVDLYRK 390

  Fly   402 IHANIAVLEHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDWKEYFRKALFGMRLYLTKE 466
            ||.|||||..|.:.:|:|:..:|..||..||.:||.||:|||..|||.:||:.|::|||||:.||
  Fly   391 IHKNIAVLGPFSSTTWNFDMTNTMELREAMSKQDRNLYDFDMAQLDWNDYFKAAMYGMRLYIGKE 455

  Fly   467 PPTQESLEQGRRLFYRLKILHYSFVTLLCVIAGFLLWTLVRLFI 510
            .||.||:.:|.:|..|||:|||:|.:.|..:||::|::|.||.:
  Fly   456 KPTAESIAKGLKLRMRLKVLHYAFASSLVALAGYILYSLARLVV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14893	NP_650568.2	PLN02996	19..452	CDD:215538	265/432 (61%)
		FAR-N_SDR_e	23..339	CDD:187547	194/315 (62%)
		Sterile	375..465	CDD:281068	54/89 (61%)
CG17560	NP_650567.1	PLN02996	1..441	CDD:215538	270/439 (62%)
		FAR-N_SDR_e	12..327	CDD:187547	193/314 (61%)
		Sterile	364..454	CDD:281068	54/89 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466698
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26995
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	11	10.910