DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14893 and CG17562

DIOPT Version :9

Sequence 1:	NP_650568.2	Gene:	CG14893 / 42023	FlyBaseID:	FBgn0038451	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_650566.1	Gene:	CG17562 / 42021	FlyBaseID:	FBgn0038449	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	499	Identity:	310/499 - (62%)
Similarity:	394/499 - (78%)	Gaps:	0/499 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 MDNGIQGFYKDKVVFLTGATGFLGKVIIEKLLRTTEVKRIYAMMRPKRGKDIQERLAIWQKDPLF 76
            ||..||..::.|.|||||||||||||:||||||||||||||.::|||||.:|::|:..|.||.:|
  Fly     1 MDTDIQRCFRSKTVFLTGATGFLGKVVIEKLLRTTEVKRIYVLIRPKRGVEIKDRIITWSKDAVF 65

  Fly    77 EVLLKAKPDALKRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHGAATVRFNEPLHVALAINTR 141
            |:|||:||:||:|:..|||||||.||||:.:||:||.|||.||||||||||||||||||||||||
  Fly    66 ELLLKSKPEALQRVCPIAGDCLDFDLGISENDRRLLASEVQIVIHGAATVRFNEPLHVALAINTR 130

  Fly   142 GTRLMLQLAKEMLQLEAYLHISTAFSNCVIFRIEEKFYPEHLTCDANSVLAMSELLSEQMMDKLA 206
            .|:||:||||||.||||::|:|||||||||:.|:|.||||||.|.::.||||:||:|::::|.:.
  Fly   131 ATKLMIQLAKEMRQLEAFVHVSTAFSNCVIYNIKENFYPEHLNCSSDKVLAMAELMSDELLDNME 195

  Fly   207 PTLVGNFPNTYTYTKALAEDVVLREFGDLPLSIFRPSVIIATHEEPVSGWIDNLYGPIAHIYGVS 271
            ..|:|:|||||||||||||||:|:|.|.|||.||||:||||.|:||:||||||:|||:|.::||:
  Fly   196 QALLGSFPNTYTYTKALAEDVILKEAGGLPLCIFRPAVIIAAHKEPISGWIDNMYGPMAILFGVA 260

  Fly   272 HGVLRLTTYDKDGYASLVPVDYCANAALASIWQTSKDKSQRNAISQPAIYTLAPSEKNLLLNTDF 336
            .||||:.|.|....|||||||||||..||..|:|..:.::......|.||.|||.|:|.:.:.:|
  Fly   261 RGVLRIATIDHHAEASLVPVDYCANLTLACTWKTIVEGNEMGTQETPLIYQLAPIEQNKITHGEF 325

  Fly   337 IKHSLIHRNDFPLTKMIWYPFVHNISNPRIFPLAAFFYHTLPGYFYDLALRLSGRKPRLVKLYRS 401
            |:|:|..|.:.||||||||||:|.|:.|.:||||||||||||.||:||||.||||||||||:|:.
  Fly   326 IRHALDGRTNCPLTKMIWYPFIHCITVPWLFPLAAFFYHTLPAYFFDLALWLSGRKPRLVKVYQK 390

  Fly   402 IHANIAVLEHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDWKEYFRKALFGMRLYLTKE 466
            ||..:.:|..|...||.|:.::||.||..||.||||:|.|||.:|:|||||.:||.|||.:|..|
  Fly   391 IHKTLGILGPFACKSWRFDMRNTDHLRQQMSEEDRRIYYFDMVSLNWKEYFVQALRGMRQFLGNE 455

  Fly   467 PPTQESLEQGRRLFYRLKILHYSFVTLLCVIAGFLLWTLVRLFI 510
            .||.||:.||::|..|||:||:....:||.:|...||:|||:.:
  Fly   456 APTPESIAQGKKLIKRLKLLHHILQGVLCFVALLALWSLVRILV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14893	NP_650568.2	PLN02996	19..452	CDD:215538	277/432 (64%)
		FAR-N_SDR_e	23..339	CDD:187547	207/315 (66%)
		Sterile	375..465	CDD:281068	54/89 (61%)
CG17562	NP_650566.1	PLN02996	10..442	CDD:215538	278/431 (65%)
		FAR-N_SDR_e	12..329	CDD:187547	207/316 (66%)
		FAR_C	362..452	CDD:176924	55/89 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466697
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	1	0.950	-	0	Normalized mean entropy	S3821
OMA	1	1.010	-	-		QHG26995
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	12	11.860