DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14893 and far1

DIOPT Version :9

Sequence 1:	NP_650568.2	Gene:	CG14893 / 42023	FlyBaseID:	FBgn0038451	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	XP_005174372.1	Gene:	far1 / 406829	ZFINID:	ZDB-GENE-040426-2908	Length:	518	Species:	Danio rerio

Alignment Length:	510	Identity:	182/510 - (35%)
Similarity:	274/510 - (53%)	Gaps:	42/510 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IQGFYKDKVVFLTGATGFLGKVIIEKLLRTTE-VKRIYAMMRPKRGKDIQERLAIWQKDPLFEVL 79
            |..:|..|.|.:||||||:|||::|||||:.. ||..|.::|||.|:....|:|......||:.|
Zfish     4 IPEYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFDRL 68

  Fly    80 LKAKPDALKRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHGAATVRFNEPLHVALAINTRGTR 144
            .:.:||...:|..|..|...|:|.::..|::.|...:::|.|.|||:||||||..|:.:|...|:
Zfish    69 REDQPDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLATQ 133

  Fly   145 LMLQLAKEMLQLEAYLHISTAFSNCVIFRIEEKFYPEHLTCDANSVLAMSELLSEQMMDKLAPTL 209
            .|:.||..|..||.::|:|||::||....|||..||..:  |...::...|.:.::::..:.|.|
Zfish   134 KMVSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPPPV--DYRKLIDTLEWMDDKLVSLMTPRL 196

  Fly   210 VGNFPNTYTYTKALAEDVVLREFGDLPLSIFRPSVIIATHEEPVSGWIDNLYGPIAHIYGVSHGV 274
            :|..||||||||||||.:|.:|.|:|.::|.|||::.|:.:||..|||||..||.........|:
Zfish   197 LGERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGI 261

  Fly   275 LRLTTYDKDGYASLVPVDYCANAALASIWQTSKDKSQRNAISQPAIYTLAPSEKNLLL------- 332
            ||......:..|.|||||...|..||:.|.:.   |||:|  :|         ::||:
Zfish   262 LRTMRASNNAVADLVPVDVVINTTLAAAWYSG---SQRHA--RP---------RSLLVYNCTTGG 312

  Fly   333 -------NTDFIKHSLIHRNDFPLTKMIWYPFVHNISNPRIFPLAAFFYHTLPGYFYDLALRLSG 390
                   ..::...|...||  ||.:....|.|:..:|..|........|..|.:.|||.||:||
Zfish   313 INPFHWGEVEYHVISTFKRN--PLEQAFRRPNVNLTTNHLINQYWIAVSHKAPAFLYDLFLRMSG 375

  Fly   391 RKPRLVKLYRSIHANIAVLEHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDWKEYFRKA 455
            |:||::|....:|..:.|||:|.::||.:.|.:...|...|..||::::|||:..|.|.||....
Zfish   376 REPRMMKTITRLHKAMMVLEYFTSHSWVWNTDNVTMLMNQMGAEDKKVFNFDVRQLHWAEYMENY 440

  Fly   456 LFGMRLYLTKEPPTQESLEQGRRLFYRLKILHYSFVTLLCVIAGFLLWTLVRLFI 510
            ..|.:.|:..|  ....|...|:...:|:.:.|:|.|:|.|    |:|   |:||
Zfish   441 CMGTKKYVLNE--ELSGLPAARKHLNKLRNIRYTFNTVLVV----LIW---RIFI 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14893	NP_650568.2	PLN02996	19..452	CDD:215538	164/447 (37%)
		FAR-N_SDR_e	23..339	CDD:187547	123/330 (37%)
		Sterile	375..465	CDD:281068	34/89 (38%)
far1	XP_005174372.1	FAR-N_SDR_e	11..333	CDD:187547	126/339 (37%)
far1	XP_005174372.1	Sterile	360..450	CDD:308580	34/89 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593274
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850