DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17560 and FAR6

DIOPT Version :9

Sequence 1:	NP_650567.1	Gene:	CG17560 / 42022	FlyBaseID:	FBgn0038450	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001326776.1	Gene:	FAR6 / 824837	AraportID:	AT3G56700	Length:	548	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	130/507 - (25%)
Similarity:	219/507 - (43%)	Gaps:	98/507 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FFKNKTVFLTGGTGFLGKVIIEKLLR-TTEVNRIYSLIRPK----RGVPIEDRITTWAKDPVFEV 67
            |.:.|:..:||.||||.||:|||||| :.|:.:|:.|:|.|    ....:.|.|.:   ..:|::
plant    80 FLEGKSYLVTGATGFLAKVLIEKLLRESLEIGKIFLLMRSKDQESANKRLYDEIIS---SDLFKL 141

  Fly    68 LLRTKPDALQ-----RVCPIAGDCLDPDLGISQSDQRILTAEVQIVIHGAATVRFDEALHISLAI 127
            |.:....:.:     ::.|:.||..:.:|||......:::.|:.::|.......||:....:|::
plant   142 LKQMHGSSYEAFMKRKLIPVIGDIEEDNLGIKSEIANMISEEIDVIISCGGRTTFDDRYDSALSV 206

  Fly   128 NVRATRLMLQLAKQMTQLVSFVHVSTAYSN------------CVVHDIAERFYPEHLNCSSDKIL 180
            |......:|...|...:|..|:|.||||..            |:..:|.     ..||..|:..|
plant   207 NALGPGRLLSFGKGCRKLKLFLHFSTAYVTGKREGTVLETPLCIGENIT-----SDLNIKSELKL 266

  Fly   181 AV-------GELVSNKLLD-AMEPSLVGSFPNTYTYTKALAEDVILREAGNLPLSIFRPAIIMST 237
            |.       |.....||.: ..|.:....:.|:||:|||:.|.||..:.||||:.|.||:||.|:
plant   267 ASEAVRKFRGREEIKKLKELGFERAQHYGWENSYTFTKAIGEAVIHSKRGNLPVVIIRPSIIESS 331

  Fly   238 YKEPLVGWVD--NLFGPLALCFGGARGIMRVTTVDPSAKISLVPADYCVNVALACAWR----TAE 296
            |.||..||:.  .:..|:.|.:  |:|.:.....||.:.:.::|.|...|.|:|...:    ..|
plant   332 YNEPFPGWIQGTRMADPIILAY--AKGQISDFWADPQSLMDIIPVDMVANAAIAAMAKHGCGVPE 394

  Fly   297 ISVQNGKVTTPPIYAFAPSENNLMSYGNFIKSSIIYRDIIPLTKMLWYPFVLCISTTSLFPLAAF 361
            ..|.|         ..:.|..|.|..|..|..|..:....||.:             ::..|...
plant   395 FKVYN---------LTSSSHVNPMRAGKLIDLSHQHLCDFPLEE-------------TVIDLEHM 437

  Fly   362 FLH-TLPGYFFDLL----------------LRLKGRKPILVDLYRKIHKNIAVLGPFSSTTW--- 406
            .:| :|.|:...|.                |..||:        ||::..:::...:...|:
plant   438 KIHSSLEGFTSALSNTIIKQERVIDNEGGGLSTKGK--------RKLNYFVSLAKTYEPYTFFQA 494

  Fly   407 NFDMTNTMELREAMSKQDRNLYDFDMAQLDWNDYF-KAAMYGMRL-YIGKEK 456
            .||.|||..|.:.||.:::..:.||:..:||..|. ...:.|::. ::.|:|
plant   495 RFDNTNTTSLIQEMSMEEKKTFGFDIKGIDWEHYIVNVHLPGLKKEFLSKKK 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17560	NP_650567.1	PLN02996	1..441	CDD:215538	126/488 (26%)
		FAR-N_SDR_e	12..327	CDD:187547	98/350 (28%)
		Sterile	364..454	CDD:281068	24/111 (22%)
FAR6	NP_001326776.1	PLN02996	77..539	CDD:215538	128/498 (26%)
		FAR-N_SDR_e	84..426	CDD:187547	100/360 (28%)
		FAR_C	<471..539	CDD:176924	19/75 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.970