DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17560 and Far1

DIOPT Version :9

Sequence 1:	NP_650567.1	Gene:	CG17560 / 42022	FlyBaseID:	FBgn0038450	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001272760.1	Gene:	Far1 / 67420	MGIID:	1914670	Length:	515	Species:	Mus musculus

Alignment Length:	499	Identity:	166/499 - (33%)
Similarity:	265/499 - (53%)	Gaps:	20/499 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IQGFFKNKTVFLTGGTGFLGKVIIEKLLRT-TEVNRIYSLIRPKRGVPIEDRITTWAKDPVFEVL 68
            |..:::.|.:.|||.|||||||::|||||: ..||.:|.|:|.|.|...::|:.......:|:.|
Mouse     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSKLFDRL 68

  Fly    69 LRTKPDALQRVCPIAGDCLDPDLGISQSDQRILTAEVQIVIHGAATVRFDEALHISLAINVRATR 133
            ....||..:::..|..:...|.|.:|:.|:.|:.....::.|.||||||:|.|..::.:||.|||
Mouse    69 RDENPDFREKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   134 LMLQLAKQMTQLVSFVHVSTAYSNCVVHDIAERFYPEHLNCSSDKILAVGELVSNKLLDAMEPSL 198
            .::.||:||..|..|:||||||:.|....|.|..||..::  ..|::...|.:.:.|::.:.|.|
Mouse   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVD--PKKLIDSLEWMDDGLVNDITPKL 196

  Fly   199 VGSFPNTYTYTKALAEDVILREAGNLPLSIFRPAIIMSTYKEPLVGWVDNLFGPLALCFGGARGI 263
            :|..||||.|||||||.|:.:|...|.::|.||:|:.:::|||..||:||..||..|.....:||
Mouse   197 IGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   264 MRVTTVDPSAKISLVPADYCVNVALACAW-----RTAEISVQNGKVTTPPIYAFAPSENNLMSYG 323
            :|......:|...|||.|..||.:||.||     |...|.|.|  .||.....|...|     .|
Mouse   262 LRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNRPRNIMVYN--CTTGSTNPFHWGE-----VG 319

  Fly   324 NFIKSSIIYRDIIPLTKMLWYPFVLCISTTSLFPLAAFFLHTLPGYFFDLLLRLKGRKPILVDLY 388
            :::..|.   .:.||.::..:|:|...|...:........||:|....||.|||.|:||.::...
Mouse   320 DYLNHSF---KMNPLNQVFRHPYVKFCSNNLMLHYWKGVKHTVPALLLDLALRLTGQKPWMMKTI 381

  Fly   389 RKIHKNIAVLGPFSSTTWNFDMTNTMELREAMSKQDRNLYDFDMAQLDWNDYFKAAMYGMRLYIG 453
            .::||.:..|..|:|.:|.::..|...|...::.:|:..::.|:.||.|.:|.:....|.:.|:.
Mouse   382 TRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVL 446

  Fly   454 KEKPTAESIAKGLKLRMRLKVLHYAFASSLVALAGYILYSLARL 497
            .|:.:....|:  |...:|:.:.|.|.:.||.|...|..:.:::
Mouse   447 NEEMSGLPAAR--KHLNKLRNIRYGFNTILVILIWRIFIARSQM 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17560	NP_650567.1	PLN02996	1..441	CDD:215538	153/441 (35%)
		FAR-N_SDR_e	12..327	CDD:187547	122/320 (38%)
		Sterile	364..454	CDD:281068	27/89 (30%)
Far1	NP_001272760.1	FAR-N_SDR_e	11..330	CDD:187547	123/330 (37%)
Far1	NP_001272760.1	Sterile	371..447	CDD:376978	19/75 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847916
Domainoid	1	1.000	96	1.000	Domainoid score	I7295
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750