Protein Alignment CG17560 and FAR2

DIOPT Version :10

• Sequence 1: NP_650567.1
• Gene: CG17560 / 42022
• FlyBaseID: FBgn0038450
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_011519049.1
• Gene: FAR2 / 55711
• HGNCID: 25531
• Length: 535
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 169/504 - (33%)
• Similarity: 272/504 - (53%)
• Gaps: 26/504 - (5%)

  Fly     3 SEIQGFFKNKTVFLTGGTGFLGKVIIEKLLRTT-EVNRIYSLIRPKRGVPIEDRITTWAKDPVFE 66
            |.|..|:..|::.:||.|||||||::|||.||: ::..||.|:|||.|..::.|:.......:||
Human    22 STIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFE 86

  Fly    67 VLLRTKPDALQRVCPIAGDCLDPDLGISQSDQRILTAEVQIVIHGAATVRFDEALHISLAINVRA 131
            .:....|:..:::..|..|....|..||:.|.:.|.:...|:.|.|||||||:.|..::.:||.|
Human    87 KVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVTA 151

  Fly   132 TRLMLQLAKQMTQLVSFVHVSTAYSNCVVHDIAERFYPEHLNCSSD--KILAVGELVSNKLLDAM 194
            ||.:|.:|.||.:|.:|:|:|||||||.:..|.|..||    |..:  ||:...|.:.:.::|.:
Human   152 TRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYP----CPVEPKKIIDSLEWLDDAIIDEI 212

  Fly   195 EPSLVGSFPNTYTYTKALAEDVILREAGNLPLSIFRPAIIMSTYKEPLVGWVDNLFGPLALCFGG 259
            .|.|:..:||.|||||||.|.|:.:|:.||.::|.||:|:.:|::||..|||||:.||..:....
Human   213 TPKLIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIAT 277

  Fly   260 ARGIMRVTTVDPSAKISLVPADYCVNVALACAWRTAEISVQNGKVTTPPIYAFAPSENNLMSYGN 324
            .:|.:|.....|.|...::|.|..||:.||..|.||   |...|.|.  :|.......|..::..
Human   278 GKGFLRAIKATPMAVADVIPVDTVVNLMLAVGWYTA---VHRPKSTL--VYHITSGNMNPCNWHK 337

  Fly   325 FIKSSIIYRDIIPLTKMLWYPF------VLCISTTSLFPLAAFFLHTLPGYFFDLLLRLKGRKPI 383
            .....:...:.||..:    ||      ....|.||.:..|.  .|..|...:|..|||.||||.
Human   338 MGVQVLATFEKIPFER----PFRRPNANFTSNSFTSQYWNAV--SHRAPAIIYDCYLRLTGRKPR 396

  Fly   384 LVDLYRKIHKNIAVLGPFSSTTWNFDMTNTMELREAMSKQDRNLYDFDMAQLDWNDYFKAAMYGM 448
            :..|..::.:.:::|..|.:.:|.:...||..|...:|.:|:.:::||:.||:|.:|.:..:.|:
Human   397 MTKLMNRLLRTVSMLEYFINRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQLNWLEYIENYVLGV 461

  Fly   449 RLYIGKEKPTAESIAKGLKLRMRLKVLHYAFASSLVALAGYILYSLARL 497
            :.|:.||  ....|.|..:...||:.:||.|.::|..:|..:|.:.:::
Human   462 KKYLLKE--DMAGIPKAKQRLKRLRNIHYLFNTALFLIAWRLLIARSQM 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17560	NP_650567.1	FAR-N_SDR_e	12..327	CDD:187547	119/317 (38%)
		Sterile	363..454	CDD:460779	27/90 (30%)
FAR2	XP_011519049.1	FAR-N_SDR_e	31..335	CDD:187547	119/312 (38%)
		Sterile	377..467	CDD:460779	27/89 (30%)