DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17560 and far1

DIOPT Version :9

Sequence 1:	NP_650567.1	Gene:	CG17560 / 42022	FlyBaseID:	FBgn0038450	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	XP_005174372.1	Gene:	far1 / 406829	ZFINID:	ZDB-GENE-040426-2908	Length:	518	Species:	Danio rerio

Alignment Length:	505	Identity:	171/505 - (33%)
Similarity:	267/505 - (52%)	Gaps:	29/505 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IQGFFKNKTVFLTGGTGFLGKVIIEKLLRTTE-VNRIYSLIRPKRGVPIEDRITTWAKDPVFEVL 68
            |..::..|.|.:||.|||:|||::|||||:.. |...|.|:|||.|...:.||.......:|:.|
Zfish     4 IPEYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFDRL 68

  Fly    69 LRTKPDALQRVCPIAGDCLDPDLGISQSDQRILTAEVQIVIHGAATVRFDEALHISLAINVRATR 133
            ...:||...::..|..|...|:|.:|..||..||..:.:|.|.|||:||:|.|..::.:||.||:
Zfish    69 REDQPDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLATQ 133

  Fly   134 LMLQLAKQMTQLVSFVHVSTAYSNCVVHDIAERFYPEHLNCSSDKILAVGELVSNKLLDAMEPSL 198
            .|:.||.:|..|..|:||||||:||....|.|..||..::..  |::...|.:.:||:..|.|.|
Zfish   134 KMVSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPPPVDYR--KLIDTLEWMDDKLVSLMTPRL 196

  Fly   199 VGSFPNTYTYTKALAEDVILREAGNLPLSIFRPAIIMSTYKEPLVGWVDNLFGPLALCFGGARGI 263
            :|..||||||||||||.::.:|.|||.::|.||:|:.:::|||..||:||..||..:.....:||
Zfish   197 LGERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGI 261

  Fly   264 MRVTTVDPSAKISLVPADYCVNVALACAW--------RTAEISVQNGKVTTPPIYAFAPSENNLM 320
            :|......:|...|||.|..:|..||.||        |...:.|.|  .||..|..|...|....
Zfish   262 LRTMRASNNAVADLVPVDVVINTTLAAAWYSGSQRHARPRSLLVYN--CTTGGINPFHWGEVEYH 324

  Fly   321 SYGNFIKSSIIYRDIIPLTKMLWYPFVLCISTTSLFPLAAFFL---HTLPGYFFDLLLRLKGRKP 382
            ....|.::        ||.:....|.|   :.|:...:..:::   |..|.:.:||.||:.||:|
Zfish   325 VISTFKRN--------PLEQAFRRPNV---NLTTNHLINQYWIAVSHKAPAFLYDLFLRMSGREP 378

  Fly   383 ILVDLYRKIHKNIAVLGPFSSTTWNFDMTNTMELREAMSKQDRNLYDFDMAQLDWNDYFKAAMYG 447
            .::....::||.:.||..|:|.:|.::..|...|...|..:|:.:::||:.||.|.:|.:....|
Zfish   379 RMMKTITRLHKAMMVLEYFTSHSWVWNTDNVTMLMNQMGAEDKKVFNFDVRQLHWAEYMENYCMG 443

  Fly   448 MRLYIGKEKPTAESIAKGLKLRMRLKVLHYAFASSLVALAGYILYSLARL 497
            .:.|:..|:.:....|:  |...:|:.:.|.|.:.||.|...|..:.:::
Zfish   444 TKKYVLNEELSGLPAAR--KHLNKLRNIRYTFNTVLVVLIWRIFIARSQM 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17560	NP_650567.1	PLN02996	1..441	CDD:215538	158/447 (35%)
		FAR-N_SDR_e	12..327	CDD:187547	127/323 (39%)
		Sterile	364..454	CDD:281068	28/89 (31%)
far1	XP_005174372.1	FAR-N_SDR_e	11..333	CDD:187547	127/333 (38%)
far1	XP_005174372.1	Sterile	360..450	CDD:308580	28/89 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593279
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850