DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17560 and CG10096

DIOPT Version :9

Sequence 1:	NP_650567.1	Gene:	CG17560 / 42022	FlyBaseID:	FBgn0038450	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	269/497 - (54%)
Similarity:	359/497 - (72%)	Gaps:	3/497 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDSEIQGFFKNKTVFLTGGTGFLGKVIIEKLLRTTEVNRIYSLIRPKRGVPIEDRITTWAKDPVF 65
            |.:::|.|:|:||||||||:||||||.|.|||.||||.|||.|:|.|||..:.:|...|.|||||
  Fly     1 MATDVQSFYKDKTVFLTGGSGFLGKVTIAKLLCTTEVKRIYVLLRAKRGQEMRERCAAWDKDPVF 65

  Fly    66 EVLLRTKPDALQRVCPIAGDCLDPDLGISQSDQRILTAEVQIVIHGAATVRFDEALHISLAINVR 130
            ..|::|.|:||:||.|..|||.:||||:|.||:::|..|||||||.||||||.|.|||:||:|.|
  Fly    66 GNLMKTNPEALKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNTR 130

  Fly   131 ATRLMLQLAKQMTQLVSFVHVSTAYSNCVVHDIAERFYPEHLNCSSDKILAVGELVSNKLLDAME 195
            |||||:||||:|:.|.||||||||||||||..::||||||||.|.::|||.:.|.:|.:|||.|.
  Fly   131 ATRLMIQLAKEMSHLESFVHVSTAYSNCVVEHVSERFYPEHLTCPAEKILELLESISPELLDKMA 195

  Fly   196 PSLVGSFPNTYTYTKALAEDVILREAGNLPLSIFRPAIIMSTYKEPLVGWVDNLFGPLALCFGGA 260
            |:|:|.:||||||||||.|.||.:||.:||||||||.:|:::||||:.||:|||:||:|:.:|.|
  Fly   196 PALMGKYPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNLYGPIAVLYGAA 260

  Fly   261 RGIMRVTTVDPSAKISLVPADYCVNVALACAWRTA-EISVQNGKVTTPPIYAFAPSENNLMSYGN 324
            .||:.:|.::..|:..:||.|||||:.|.|||.|| :.|::..  ..||||.|.|:.:||:::|.
  Fly   261 FGILHITLLNLKAQAGIVPVDYCVNMVLTCAWNTARDTSIKLS--PEPPIYNFTPNNDNLITWGG 323

  Fly   325 FIKSSIIYRDIIPLTKMLWYPFVLCISTTSLFPLAAFFLHTLPGYFFDLLLRLKGRKPILVDLYR 389
            |...:...|...|||||:|.||:.|.:...||...|.|.|.||||..||.|||.|:||.::.||.
  Fly   324 FRDKAARLRYTYPLTKMMWLPFLHCTTIPWLFRFTAIFYHLLPGYAIDLALRLWGKKPRMIKLYD 388

  Fly   390 KIHKNIAVLGPFSSTTWNFDMTNTMELREAMSKQDRNLYDFDMAQLDWNDYFKAAMYGMRLYIGK 454
            ||||||.:|.||..|:|:||..||.:|...||.:|:.||||:|:.:||:|||..|:.|:|:|:.|
  Fly   389 KIHKNIDILAPFVITSWSFDTVNTRKLWAKMSVEDQKLYDFNMSSVDWDDYFLQALAGVRIYLAK 453

  Fly   455 EKPTAESIAKGLKLRMRLKVLHYAFASSLVALAGYILYSLAR 496
            |:|..|.:.:|.|:..|.:.||.....:|...|..||:|:.:
  Fly   454 EEPGQEVVERGRKIYKRFEFLHRLLQFTLCGGAALILWSILK 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17560	NP_650567.1	PLN02996	1..441	CDD:215538	249/440 (57%)
		FAR-N_SDR_e	12..327	CDD:187547	189/315 (60%)
		Sterile	364..454	CDD:281068	48/89 (54%)
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	250/441 (57%)
		FAR-N_SDR_e	12..330	CDD:187547	189/319 (59%)
		Sterile	363..453	CDD:281068	48/89 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466701
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.890