DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17560 and CG1441

DIOPT Version :9

Sequence 1:	NP_650567.1	Gene:	CG17560 / 42022	FlyBaseID:	FBgn0038450	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	481	Identity:	164/481 - (34%)
Similarity:	258/481 - (53%)	Gaps:	18/481 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DSEIQGF---FKNKTVFLTGGTGFLGKVIIEKLLRTT-EVNRIYSLIRPKRGVPIEDRITTWAKD 62
            |:|:...   ||.:::|:||||||||||::|||||:. .:.|||.|||||:|...::||....::
  Fly    22 DNEVDRIAECFKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERIKDIFQN 86

  Fly    63 PVFEVL--LRTKPDALQRVCPIAGDCLDPDLGISQSDQRILTAEVQIVIHGAATVRFDEALHISL 125
            .:|:.:  :|.:...||:|..||||.|.|.||||:.|...|..||.||.|.||||||||.|..::
  Fly    87 VLFDQVKQMRGEEHILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPLRNAV 151

  Fly   126 AINVRATRLMLQLAKQMTQLVSFVHVSTAYSNCVVHDIAERFYPEHLNCSSDKILAVGELVSNKL 190
            .:|.|.|:.||:||..:..|..|.:.||||.:..|..:.|:  |........|::...|.:::..
  Fly   152 FMNTRGTKYMLELALTLKHLDFFAYCSTAYCHLHVKTLYEK--PYDPPADPHKVMQACEWLTDDE 214

  Fly   191 LDAMEPSLVGSFPNTYTYTKALAEDVILREAGNLPLSIFRPAIIMSTYKEPLVGWVDNLFGPLAL 255
            :..:|..::|:.||||.|||:|||.:::.:...||..|.||:|::..:|||:.||.||:.||..|
  Fly   215 VATIERKVLGAIPNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNINGPTGL 279

  Fly   256 CFGGARGIMRVTTVDPSAKISLVPADYCVNVALACAWRTAEISVQNGKVTTPPIYAFAPSENNLM 320
            ..|..:|::|....:.|.....:|.|..||..|..:||    ::..|...|..:.....|.:..:
  Fly   280 LIGAGKGVIRTMYCNSSGYGDFLPVDVAVNGILVASWR----NITAGTDKTNRVAHMTSSNDIKV 340

  Fly   321 SYGNFIK-SSIIYRDIIPLTKMLWYPFVLCISTTSLFPLAAFFLHTLPGYFFDLLLRLKGRKPIL 384
            |:...|: ...:..:.:||..:.|||.....|...:..:.......:|..|.|.||.:....|:|
  Fly   341 SWAEIIELGRWVIENKVPLNGVAWYPGGSMKSNYWVHFICMVLFQWMPALFVDALLWILRYPPVL 405

  Fly   385 VDLYRKIHKNIAVLGPFSSTTWNFDMTNTMELREAMSKQDRNLYDFDMAQLDWNDYFKAAMYGMR 449
            ..:..:|:|...|...:::..||||.:..::||:.|:.::|..|..:..:||..|||...:...|
  Fly   406 CRVQNRIYKGFEVFEYYANNVWNFDNSEAVKLRKLMNNKERRTYVIEKIELDLIDYFTNCVLCAR 470

  Fly   450 LYIGKEKPTAESIAKGLKLRMRLKVL 475
            ..|.||  :.|||...   |..:||:
  Fly   471 RLILKE--SDESIPAA---RRHMKVM 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17560	NP_650567.1	PLN02996	1..441	CDD:215538	152/445 (34%)
		FAR-N_SDR_e	12..327	CDD:187547	119/317 (38%)
		Sterile	364..454	CDD:281068	26/89 (29%)
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	153/445 (34%)
		FAR-N_SDR_e	35..348	CDD:187547	120/318 (38%)
		Sterile	385..475	CDD:281068	26/89 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466779
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	10	9.900