Protein Alignment CG17562 and Far1

DIOPT Version :10

• Sequence 1: NP_650566.1
• Gene: CG17562 / 42021
• FlyBaseID: FBgn0038449
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_081655.2
• Gene: Far1 / 67420
• MGIID: 1914670
• Length: 515
• Species: Mus musculus
• Alignment Length: 491
• Identity: 161/491 - (32%)
• Similarity: 257/491 - (52%)
• Gaps: 14/491 - (2%)

  Fly     5 IQRCFRSKTVFLTGATGFLGKVVIEKLLRT-TEVKRIYVLIRPKRGVEIKDRIITWSKDAVFELL 68
            |...:..|.:.|||||||||||::|||||: ..|..:|||:|.|.|...::|:.......:|:.|
Mouse     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSKLFDRL 68

  Fly    69 LKSKPEALQRVCPIAGDCLDFDLGISENDRRLLASEVQIVIHGAATVRFNEPLHVALAINTRATK 133
            ....|:..:::..|..:.....|.:||.|:.::.....::.|.||||||||.|..|:.:|..||:
Mouse    69 RDENPDFREKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   134 LMIQLAKEMRQLEAFVHVSTAFSNCVIYNIKENFYPEHLNCSSDKVLAMAELMSDELLDNMEQAL 198
            .:|.||::|:.||.|:|||||::.|...:|.|..||..::  ..|::...|.|.|.|::::...|
Mouse   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVD--PKKLIDSLEWMDDGLVNDITPKL 196

  Fly   199 LGSFPNTYTYTKALAEDVILKEAGGLPLCIFRPAVIIAAHKEPISGWIDNMYGPMAILFGVARGV 263
            :|..||||.|||||||.|:.:|...|.:.|.||:::.|:.|||..|||||..||..:.....:|:
Mouse   197 IGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   264 LRIATIDHHAEASLVPVDYCANLTLACTWKTIVEGNEMGTQETPLIYQLAPIEQNKITHGEFIRH 328
            ||.....::|.|.|||||...|.:||..|.:.|     ......::|.......|....||...|
Mouse   262 LRTMRASNNALADLVPVDVVVNTSLAAAWYSGV-----NRPRNIMVYNCTTGSTNPFHWGEVEYH 321

  Fly   329 ALDGRTNCPLTKMIWYPFIHCITVPWLFPLAAFFYHTLPAYFFDLALWLSGRKPRLVKVYQKIHK 393
            .:......||.:....|.::..:...|:.......|..||:.:|:.|.::||.||::|...::||
Mouse   322 VISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPRMMKTITRLHK 386

  Fly   394 TLGILGPFACKSWRFDMRNTDHLRQQMSEEDRRIYYFDMVSLNWKEYFVQALRGMRQFLGNEAPT 458
            .:..|..|...||.::..|.:.|..|::.||::.:..|:..|:|.||......|.::::.||..:
Mouse   387 AMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVLNEEMS 451

  Fly   459 PESIAQGKKLIKRLKLLHHILQGVLCFVALLALWSL 494
            ....|:     |.|..|.:|..|....:.:| :|.:
Mouse   452 GLPAAR-----KHLNKLRNIRYGFNTILVIL-IWRI 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17562	NP_650566.1	FAR-N_SDR_e	12..329	CDD:187547	118/317 (37%)
		Sterile	363..452	CDD:460779	27/88 (31%)
Far1	NP_081655.2	FAR-N_SDR_e	11..330	CDD:187547	119/325 (37%)
		Sterile	357..447	CDD:460779	27/89 (30%)
		Necessary and sufficient for PEX19-mediated localization into peroxisome membrane. /evidence=ECO:0000250|UniProtKB:Q8WVX9	451..507		8/37 (22%)