DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17562 and CG8306

DIOPT Version :9

Sequence 1:	NP_650566.1	Gene:	CG17562 / 42021	FlyBaseID:	FBgn0038449	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_611140.3	Gene:	CG8306 / 36857	FlyBaseID:	FBgn0034142	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	155/505 - (30%)
Similarity:	257/505 - (50%)	Gaps:	42/505 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FRSKTVFLTGATGFLGKVVIEKLLR-TTEVKRIYVLIRPKRGVEIKDRIITWSKDAVF----ELL 68
            :..:.||:||||||:|..::||||| ...|..:|:|:|.|:|..:::|:....|::||    ||.
  Fly    10 YAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERLEELKKNSVFDKFKELQ 74

  Fly    69 LKSKPEALQRVCPIAGDCLDFDLGISENDRRLLASEVQIVIHGAATVRFNEPLHVALAINTRATK 133
            |:|:   |.::.||.||.....||||..||:.|...|.:|.|.|||:.|.:.|.....||.|.|:
  Fly    75 LQSR---LSKIVPIEGDVGLEHLGISPKDRQTLIDNVNVVFHSAATLDFFQSLKETTNINLRGTR 136

  Fly   134 LMIQLAKEMRQLEAFVHVSTAFSNCVIYNIKENFYPEHLNCSSDKVLAMAELMSDELLDNMEQAL 198
            .:::|.::::.|:|.||||:|:.|..:..::|..||...:  .:|::.::|.::|:.|..:|..|
  Fly   137 RVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYPAPED--PEKIIQLSETLNDDALKELEPKL 199

  Fly   199 LGSFPNTYTYTKALAEDVILKEAGGLPLCIFRPAVIIAAHKEPISGWIDNMYGPMAILFGVARGV 263
            |...|||||:||.|||..:...|...|..|.||::|.||.||||.||..:..||.....|.::||
  Fly   200 LKDHPNTYTFTKHLAEHEVANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGASKGV 264

  Fly   264 LRIATIDHHAEASLVPVDYCAN-LTLACTWKTIVEGNEMG----------TQET--PLIYQLAPI 315
            ||...:|.......:|:|...| :.....:...::....|          |..|  |..::|...
  Fly   265 LRRLPLDPSIIMDYIPIDVVVNGIITTGYYVNSLQAKNGGRPADLQIFHLTSSTYKPFRFELMTD 329

  Fly   316 EQNKITHGEFIRHALDGRTNCPLTKMIWYPFIHCITVPWLFPLAAFFYHTLPAYFFDLALWLSGR 380
            :.|...|            :.||...:|||.:..:...|:|.|:|..:|.:||...||...:.|.
  Fly   330 KINSYLH------------DYPLNSAVWYPNLRLVKSLWVFRLSAILFHFIPAIILDLVTKIGGG 382

  Fly   381 KPRLVKVYQKIHKTLGILGPFACKSWRFDMRNTDHLRQQMSEEDRRIYYFDMVSLNWKEYFVQAL 445
            :|.||::::.:..:|..|..|....|.||.:....|.:.::..|::.::.|:..|.|.|||...:
  Fly   383 RPILVRLHKNVWNSLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDEYFSNTI 447

  Fly   446 RGMRQFLGNE-------APTPESIAQGKKLIKRLKLLHHILQGVLCFVAL 488
            .|:||:|..|       |...:.|..|..:..:|...:.:.:.::|...:
  Fly   448 LGVRQYLSKEPIKNLEKARRKDKILLGLHVALQLSFWYGVFKLIVCLTGI 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17562	NP_650566.1	PLN02996	10..442	CDD:215538	144/449 (32%)
		FAR-N_SDR_e	12..329	CDD:187547	113/334 (34%)
		FAR_C	362..452	CDD:176924	26/89 (29%)
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	149/462 (32%)
		FAR-N_SDR_e	13..339	CDD:187547	113/342 (33%)
		FAR_C	364..454	CDD:176924	26/89 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466802
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	10	9.900