DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12783 and CG31103

DIOPT Version :9

Sequence 1:	NP_001262644.2	Gene:	CG12783 / 42019	FlyBaseID:	FBgn0038448	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001097914.1	Gene:	CG31103 / 43030	FlyBaseID:	FBgn0051103	Length:	506	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	151/500 - (30%)
Similarity:	243/500 - (48%)	Gaps:	24/500 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FDSVMEDIGFGRVHLFATVTLGLLQMLTIQETMGMGIIGPAAVCDLRMNEAQLASLTAAGFMGII 68
            :|.|:|.||:|:......:..|||.:.::.....|.||..|:.|:....:|:...:.||...||.
  Fly    17 YDMVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGVMMAASVTGIF 81

  Fly    69 CSSYFWGYITDKKGRRWTLLRTITISNLCSLASMFTVTFTGFFVMRFITCIFVAGPSFVAATYLS 133
            .|:|.||||:|..|||..||.....||......||..:...|.::..:..|.|...|.....|||
  Fly    82 LSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINLLVGISVGAVSAALYAYLS 146

  Fly   134 EFCSHRIMVRSITHLYMFTGFAMISCPAWATLFLSSGLIEFEEKLVGSLTLRPWRVLGCLYILPG 198
            ||...|....:|.:..||.....|..||.|.|.|||..    ...:|....||||:|..:.:|||
  Fly   147 EFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNW----AITMGDFVFRPWRLLLLVSLLPG 207

  Fly   199 VVAFLLLLLLPESPKFLLMIGETKRGLDTMEWISRKNTGRT----LSEDQMKRLLAYQEHVQVKR 259
            .:..|:||..||||||||...:....::.:.|||:.|.|::    ||.|:.  .|..::.|....
  Fly   208 FIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEF--TLKSEDPVGENL 270

  Fly   260 RKEHQ--NFFRSMLDDAMPLVRKPYGGYFTCVCMVMFVLGLLTHGLGIWYTAMRNRCNMRQGNTN 322
            ..|.|  .....:....:||..||:|..|....:.:|.:...::|:.:|:..:.||.:..:.|::
  Fly   271 LGESQGCGILSKICRATIPLFHKPHGFNFILCNLALFGMFFSSNGMQLWFPEIVNRSSGAENNSS 335

  Fly   323 GMTFCQVLFVPETGPFIETESDLDVVCSD--SFKGFNDSFVLGFVYVVLYNISWASLFCVHKKVM 385
              |.|::|.||...|.: ||: ||  |:|  |.|.:.|:.|:||.:::.::|....|..:.:|.:
  Fly   336 --TVCEILSVPVEQPNV-TET-LD--CTDPISSKTYIDNLVVGFAFLIGFSIQGLILNPLGRKNV 394

  Fly   386 FVFSLVASSTFGFLLIF--ATNHMLQLFSLVFLIAFPGIIIGLLGGSLLVFVPTYLRGKALCISL 448
            .:.:|..::..|.||.|  :...:|.||.|..|:  ||:.|.::.|:::..|||:||.||:...:
  Fly   395 LLAALAVATLSGVLLHFMESPTGVLVLFCLYILL--PGLSISIMIGAIVDLVPTHLRSKAVSFCM 457

  Fly   449 MWCRCGAAFGAMLVGSKIQYNCELFLLAISILPLIAACMEGYLPL 493
            ...|.|......|:|..:|..|.......:...::...:..|||:
  Fly   458 SLGRLGIIAATNLMGVMLQPYCNTTFAMFTCTLIVCIVIVHYLPI 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12783	NP_001262644.2	synapt_SV2	<2..>310	CDD:130366	97/311 (31%)
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	140/459 (31%)
CG31103	NP_001097914.1	MFS	34..>189	CDD:119392	50/158 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473171
Domainoid	1	1.000	45	1.000	Domainoid score	I3556
eggNOG	1	0.900	-	-		E33208_3BJZM
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	1	1.000	-	-		FOG0009986
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900