DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10345 and scarb2b

DIOPT Version :9

Sequence 1:	NP_650563.2	Gene:	CG10345 / 42017	FlyBaseID:	FBgn0027562	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_009299911.1	Gene:	scarb2b / 564077	ZFINID:	ZDB-GENE-170406-1	Length:	523	Species:	Danio rerio

Alignment Length:	507	Identity:	133/507 - (26%)
Similarity:	231/507 - (45%)	Gaps:	61/507 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ALGMTLLFFGSLVIISDPLQSI----LDTQLSLKPGTLLHRLWLLPPLDVYINVYMFNYTNVDEF 79
            |.|..||..|..:..|...|::    |..:::|..|:.:...|..||..||:..:.||.||.:.|
Zfish    13 AAGALLLLAGIALFASGLFQTLIHNKLKKEITLTEGSKVFATWKNPPPPVYMEFFFFNVTNPEAF 77

  Fly    80 TSGRASKLQLQEVGPYVYKEVLSNHNVTYNESNNTI-TYSPKREYVFAPERSVGDPKIDRIRAPN 143
            ..|.| |.:|.|:|||.|:|....|||::.::...: .|:|| .:||.||:|||||.:|.:...|
Zfish    78 LKGEA-KARLSEMGPYTYREYRPKHNVSFVDNGTKVAAYTPK-VFVFVPEKSVGDPSVDMVTTVN 140

  Fly   144 IPLMGVTTLASSLSMFAALGLSAITRQLNSQPMLEMSVHDYMWGYEDHLVELASRFVPNWIDFSS 208
            ||.:.|...........:..:|...:.:.::..:..:|.:.:||::|.|:.......|...:|
Zfish   141 IPAVAVMNRIKGAGFLVSSAMSLYMKSIGAEMFMTHTVDELLWGFKDPLLTKLRSIKPETDEF-- 203

  Fly   209 FGIMEKLFREGNESNVFNMNLPEPKDKYGMRMTDAPRGYTVDSINGERGFKGWQYNEET--NGTM 271
            ||:|  |.:.|::...|..:..|      ....|..|.:|   ..||:....|:.|:..  |||
Zfish   204 FGLM--LHKNGSDDGEFVYHTGE------HNYLDYGRIFT---WKGEKLMSFWKTNQSNMINGT- 256

  Fly   272 CNRIWGSHDATLFPLDMDENDEFFLYRRTFCRRLPVKFNRTTTFNGLDAFEFVMEPDSFDSEVDN 336
                    |.:.|...:.:.:...::....||.:.::|.:.....|:.|:.|........|..:|
Zfish   257 --------DGSAFHPFLTKEERLDVFTADLCRSIHMRFEKEVEVKGIPAYRFTPPRAVLASGTNN 313

  Fly   337 ANSSCYCKN-NRCLKKGVGNVSPCYYNIPLAITYPHFMHADPSLLEPFDGLQPNVSRFTSTFV-V 399
            ..:..:|.. .:||..||.:||.|....|:.:::|||...|...::..:||.| |.....||: :
Zfish   314 PENEGFCLTPKKCLDDGVLDVSVCRQGAPVVVSFPHFHLGDEKYVQAVEGLSP-VHEQHQTFLDL 377

  Fly   400 QPQLGAPMQGTHLRLQANQVVGKVNFNRMMTPFENMILPLLWVDLNIDV----------LCLTLR 454
            .|.:|.|::... |.|.|..:.:|....|....|:.|.|:::::.::.:          |.|.:.
Zfish   378 NPTMGVPVRAMK-RAQINIHLERVTGFPMTRNLESTIFPIIFLNESVVIDNASAERIQKLLLVVT 441

  Fly   455 LLIHGIKWGFPLLQWSAALGMLLAGVYQLCSALLLCFWPTARQFQKVDQVER 506
            |:.|     |||:  ..|||::|     |..|::|    ..|.:|...:|:|
Zfish   442 LVSH-----FPLI--LVALGVIL-----LIVAVIL----AVRYYQNKTEVKR 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10345	NP_650563.2	CD36	21..488	CDD:279474	127/485 (26%)
scarb2b	XP_009299911.1	CD36	30..463	CDD:279474	122/470 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.020