DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10345 and cd36

DIOPT Version :9

Sequence 1:	NP_650563.2	Gene:	CG10345 / 42017	FlyBaseID:	FBgn0027562	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001002363.1	Gene:	cd36 / 436636	ZFINID:	ZDB-GENE-040718-55	Length:	465	Species:	Danio rerio

Alignment Length:	509	Identity:	119/509 - (23%)
Similarity:	222/509 - (43%)	Gaps:	87/509 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 NQRNAKLLRSAALGMTLLFFGSLVI-ISDP-LQSILDTQLSLKPGTLLHRLWLLPPLDVYINVYM 70
            :||.| |:..|.||..:...|.::| :.|. :::.:..:..|:.|||....|....:.:|...::
Zfish     5 DQRCA-LITGAVLGALIALLGGILIPVGDMIIKNTVHKETVLENGTLAFDTWTSVDIAMYRQFWI 68

  Fly    71 FNYTNVDEFTSGRASKLQLQEVGPYVYK-EVLSNHNVTYNESNNTITYSPKREYVFAPERSVGDP 134
            ||..|.|:..| ..||..|.:.|||.|: ..:...|:|:|: |||:::.......|.|..|||..
Zfish    69 FNVENPDKVLS-EGSKPVLVQKGPYTYRVRYIPKTNITFND-NNTVSFVLPAGATFEPSMSVGSE 131

  Fly   135 KIDRIRAPNIPLMGVTTLASSLSMFAALG---LSAITRQLNSQPMLEMSVHDYMWGYEDHLV-EL 195
            : |...:.|:.:.||         :..:|   ...:.|...|......:|.:.:|||:|.:: .|
Zfish   132 E-DVFTSLNLAVAGV---------YRLIGPKLADWLIRSSGSSLFQNRTVKELLWGYKDPMLNSL 186

  Fly   196 ASRFVPNWIDFSSFGIMEKLFREGNESNVFNMNLPEPKDKYGMRMTDAPRGYTV----DSINGER 256
            ...|.|                       :|..:..|              |||    |.||...
Zfish   187 VGAFYP-----------------------YNGTVDGP--------------YTVFTGKDDINKVA 214

  Fly   257 GFKGWQYNEET-----NGTMCNRIWGSHDATLFPLDMDENDEFFLYRRTFCRRLPVKFNRTTTFN 316
            ..:.||  .||     |.:.|::|.||..::..|. :|:.:..:.:....||.:..::..|....
Zfish   215 IIERWQ--GETSVNYWNDSYCDKINGSDGSSFHPF-LDKKEPLYFFSPDICRSISAEYEATVNLK 276

  Fly   317 GLDAFEFVMEPDSFDSEVDNANSSCYCKNN----RCLKKGVGNVSPCYYNIPLAITYPHFMHADP 377
            |:|.:.:::..|:..|.|.|.::.|||.::    .|...|:.:::.| ...|:.|:.|||::|..
Zfish   277 GIDVYRYLLPVDALASPVSNPDNMCYCTDHEITRNCTLAGLLDITSC-KGTPVFISLPHFLYASI 340

  Fly   378 SLLEPFDGLQPNVSRFTSTFVVQPQLGAPMQGTHLRLQANQVVGKVNFNRMMTPF-ENMILPLLW 441
            .|.:...|:.||:...:....|:|..|..::.:. |||.|.:.|..:...::... |:.|:|:||
Zfish   341 ELQQGVVGMNPNLDEHSIFLDVEPITGFTLRFSK-RLQVNMMYGPSDDIALLNKIKEHTIIPILW 404

  Fly   442 VDLNIDVLCLTLRL----------LIHGIKWGFPLLQWSAALGMLLAGVYQLCS 485
            ::....:...|.::          ::.|::.|..:...:..||.:: |:..:||
Zfish   405 LNETAVLDDETAKMFKNELISRMDMLEGLQIGLLVTGSAIFLGCMI-GLIVVCS 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10345	NP_650563.2	CD36	21..488	CDD:279474	113/496 (23%)
cd36	NP_001002363.1	CD36	17..450	CDD:279474	110/486 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820