Protein Alignment CG14892 and KLK3

DIOPT Version :10

• Sequence 1: NP_650562.1
• Gene: CG14892 / 42016
• FlyBaseID: FBgn0038447
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 93/411 - (22%)
• Similarity: 133/411 - (32%)
• Gaps: 175/411 - (42%)

  Fly    48 TATLSWLCLLLLLPSSRQFETDCGCRPARRGPRIIAGAATNEGQFPWQASLELLHPSLGFLGHWC 112
            |.:::|:....|:.|                 ||:.|....:...|||    :|..|.|  ...|
Human     9 TLSVTWIGAAPLILS-----------------RIVGGWECEKHSQPWQ----VLVASRG--RAVC 50

  Fly   113 GAVLIHQYWILSAAHCVHNDLFNLPIPPLWTVVLGEHDRDVESGNEQRIPVEKIVMHHRY----- 172
            |.||:|..|:|:||||:.|..         .::||.|.........|...|.....|..|
Human    51 GGVLVHPQWVLTAAHCIRNKS---------VILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLL 106

  Fly   173 --------HNFKHDVVLMKLSKPADLTRASNIRRICLPFLLAESPDQAQSETVSPPSSADEDVLI 229
                    .:..||::|::||:||:||.|
Human   107 KNRFLRPGDDSSHDLMLLRLSEPAELTDA------------------------------------ 135

  Fly   230 QQLELEDVPEKIDNFLRSVQSRRRYRNVTAPSMKELMNMKILSRMRQALAQRSPRSHKRSRRRND 294
              :::.|:|
Human   136 --VKVMDLP-------------------------------------------------------- 142

  Fly   295 KLMKLGPRRDSDDSAEQKHPKVSDEPKEIAFVDCVATGWGKANISGDLSNQLLKTQVPLH--QNG 357
                                  :.||  .....|.|:|||.......|:.:.|:. |.||  .|.
Human   143 ----------------------TQEP--ALGTTCYASGWGSIEPEEFLTPKKLQC-VDLHVISND 182

  Fly   358 RCRDAYGSFVNIHGGHLCAGKLNGEGGTCVGDSGGPLQCRLSRDGPWILVGVTSFGS-GCALEGF 421
            .|...:...|...  .||||:..|...||.|||||||.|.      .:|.|:||:|| .|||...
Human   183 VCAQVHPQKVTKF--MLCAGRWTGGKSTCSGDSGGPLVCN------GVLQGITSWGSEPCALPER 239

  Fly   422 PDVYTRTSYYMKWIEDTIATH 442
            |.:||:..:|.|||:|||..:
Human   240 PSLYTKVVHYRKWIKDTIVAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14892	NP_650562.1	Tryp_SPc	81..438	CDD:238113	85/372 (23%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	85/372 (23%)