Protein Alignment CG14892 and Hpn

DIOPT Version :10

• Sequence 1: NP_650562.1
• Gene: CG14892 / 42016
• FlyBaseID: FBgn0038447
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: XP_038958886.1
• Gene: Hpn / 29135
• RGDID: 61982
• Length: 539
• Species: Rattus norvegicus
• Alignment Length: 488
• Identity: 113/488 - (23%)
• Similarity: 164/488 - (33%)
• Gaps: 189/488 - (38%)

  Fly     2 MKPSQSQLHSQSQTQSRPKSRLQSRPQSRSQSLS-------QSQCHWQI---PATSTATLSWLC- 55
            :.|..|:|....:|:...:....||..:|...|.       ::..|.::   .|.:..|..:.|
  Rat    97 LSPGDSRLLVLDKTEGTWRLLCSSRSNARVAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCV 161

  Fly    56 ----------LLLLL-----PSSRQFET----DCGCRPARRGP--RIIAGAATNEGQFPWQASLE 99
                      ||.::     |..| |.|    |||   .|:.|  ||:.|..::.|::|||.||.
  Rat   162 DEGGLPLAQRLLDVISVCDCPRGR-FLTATCQDCG---RRKLPVDRIVGGQDSSLGRWPWQVSLR 222

  Fly   100 LLHPSLGFLG-HWCGAVLIHQYWILSAAHCV--HNDLFNLPIPPLWTVVLGEHDRDVESGNEQRI 161
                   :.| |.||..|:...|:|:||||.  .|.:.:     .|.|..|...|  .|.:..::
  Rat   223 -------YDGTHLCGGSLLSGDWVLTAAHCFPERNRVLS-----RWRVFAGAVAR--TSPHAVQL 273

  Fly   162 PVEKIVMHHRYHNFK--------HDVVLMKLSKPADLTRASNIRRICLPFLLAESPDQAQSETVS 218
            .|:.::.|..|..|:        :|:.|:.||....||  ..|:.:|||
  Rat   274 GVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLT--EYIQPVCLP---------------- 320

  Fly   219 PPSSADEDVLIQQLELEDVPEKIDNFLRSVQSRRRYRNVTAPSMKELMNMKILSRMRQALAQRSP 283
                                                                             
  Rat   321 ----------------------------------------------------------------- 320

  Fly   284 RSHKRSRRRNDKLMKLGPRRDSDDSAEQKHPKVSDEPKEIAFVD---CVATGWGKANISGDLSNQ 345
                                    :|.|            |.||   |..||||.....|..:..
  Rat   321 ------------------------AAGQ------------ALVDGKVCTVTGWGNTQFYGQQAVV 349

  Fly   346 LLKTQVPLHQNGRCR--DAYGSFVNIHGGHLCAGKLNGEGGTCVGDSGGPLQC--RLSRDGPWIL 406
            |.:.:||:..|..|.  |.||:  .|.....|||...|....|.||||||..|  |:|....|.|
  Rat   350 LQEARVPIISNEVCNSPDFYGN--QIKPKMFCAGYPEGGIDACQGDSGGPFVCEDRISGTSRWRL 412

  Fly   407 VGVTSFGSGCALEGFPDVYTRTSYYMKWIEDTI 439
            .|:.|:|:||||...|.|||:...:.:||...|
  Rat   413 CGIVSWGTGCALARKPGVYTKVIDFREWIFQAI 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14892	NP_650562.1	Tryp_SPc	81..438	CDD:238113	88/374 (24%)
Hpn	XP_038958886.1	Hepsin-SRCR	92..200	CDD:462736	22/106 (21%)
		Tryp_SPc	204..441	CDD:238113	86/371 (23%)