DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scp2 and CETN3

DIOPT Version :9

Sequence 1:	NP_524381.1	Gene:	Scp2 / 42015	FlyBaseID:	FBgn0020907	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	NP_001284694.1	Gene:	CETN3 / 1070	HGNCID:	1868	Length:	191	Species:	Homo sapiens

Alignment Length:	194	Identity:	35/194 - (18%)
Similarity:	72/194 - (37%)	Gaps:	64/194 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ISDFRKKKLLFLFNVFFDVNQSGEIDVKDFELAIERVCQLRGW---QKDTPKNKETYDLMMEIWT 64
            :|:.:|:::...|.: ||.::...||..:.::|:..:    |:   :.|..|..:.|
Human    22 LSEEQKQEIKDAFEL-FDTDKDEAIDYHELKVAMRAL----GFDVKKADVLKILKDY-------- 73

  Fly    65 GLRSKADKDNDGQVSVDEWCNMWDAYAKDPSSVMDW---QNAYMNFM--FDLEDASHDGGIDVTE 124
                  |::..|:::.:::..:          |.||   ::.:...:  |.|.|....|.|.:..
Human    74 ------DREATGKITFEDFNEV----------VTDWILERDPHEEILKAFKLFDDDDSGKISLRN 122

  Fly   125 FTLVCSSYGLEKTECE-----EAFAKMSQGQ----------------------SEVTREQFAAL 161
            ...|....|...::.|     |.|.|...|:                      |||.:|:|.|:
Human   123 LRRVARELGENMSDEELRAMIEEFDKDGDGEILKNILLLPIWSRCLSLNREFFSEVNQEEFIAI 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scp2	NP_524381.1	EFh	10..87	CDD:298682	12/79 (15%)
		EF-hand_7	14..86	CDD:290234	12/74 (16%)
		FRQ1	71..163	CDD:227455	23/123 (19%)
CETN3	NP_001284694.1	PTZ00183	15..190	CDD:185503	35/194 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910