Protein Alignment CG14891 and Fbxl15

DIOPT Version :10

• Sequence 1: NP_650560.1
• Gene: CG14891 / 42013
• FlyBaseID: FBgn0038445
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001365702.1
• Gene: Fbxl15 / 68431
• MGIID: 1915681
• Length: 336
• Species: Mus musculus
• Alignment Length: 362
• Identity: 77/362 - (21%)
• Similarity: 121/362 - (33%)
• Gaps: 119/362 - (32%)

  Fly   102 PVEES------GTLSAYDLPITDDIWWKVLDYLSLNERLNFAASCERFQAIYELDSHRINHV--- 157
            |:|:|      |.:...|||..|.:...||:::.|.:.|........|:|:.:|...|:...
Mouse     4 PMEQSGGEQEPGAVRLLDLPWEDVLLPHVLNWVPLRQLLRLQRVSRAFRALVQLHLARLRRFDAA 68

  Fly   158 ----------------------LNMKDVCTLT----------HRVIKRLMLLSGKHIHCVTGGPL 190
                                  |.....|.:.          .|.....:|...:.:..:...|.
Mouse    69 QVSRGPEPRPRHAPAWVPPSPRLQASPCCAVNPSRPRVGPQIPRAALARLLRDAEGLQELALAPC 133

  Fly   191 HPNW-------PYLTEFVQLLGVS------------------CPNLTELSFFKISVSLAHMTHLF 230
            | .|       |.|....||..|:                  ||.|..|       ||||...:
Mouse   134 H-EWLSDEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRL-------SLAHCDWV- 189

  Fly   231 DG--ANGLIN----ITNISLRRC-NLKD-AHIYCLQML-SKLKSLDIRENFSIKGDS-----LKS 281
            ||  ..||.:    :..:.|..| .||| |.:|..|.. :.|:||.:..|.:: ||:     .::
Mouse   190 DGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANV-GDTAVQELARN 253

  Fly   282 LPISLEILNVSGCVDLSPKCLIQLAALSHLRELRCPGIVKFAKDNELYGRLAHYCPMLEVLELTD 346
            .| .||.|:::||:.:.                           ::....||.|||.|..|.:..
Mouse   254 CP-QLEHLDLTGCLRVG---------------------------SDGVRTLAEYCPALRSLRVRH 290

  Fly   347 FMNVIQLGGLSRLHTLVIHSSAQLDYHVNNVLLTSIA 383
            ..:|.: ..||||....:....:...|...|||..:|
Mouse   291 CHHVAE-PSLSRLRKRGVDIDVEPPLHQALVLLQDMA 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14891	NP_650560.1	RRM	41..92	CDD:214636
		leucine-rich repeat	211..237	CDD:275381	9/27 (33%)
		LRR	<235..>463	CDD:443914	39/161 (24%)
		leucine-rich repeat	239..262	CDD:275381	8/25 (32%)
		leucine-rich repeat	263..285	CDD:275381	7/26 (27%)
		leucine-rich repeat	286..338	CDD:275381	9/51 (18%)
		leucine-rich repeat	339..387	CDD:275381	12/45 (27%)
		leucine-rich repeat	388..415	CDD:275381
		leucine-rich repeat	416..439	CDD:275381
		leucine-rich repeat	440..465	CDD:275381
Fbxl15	NP_001365702.1	F-box_FBXL15	19..62	CDD:438898	11/42 (26%)
		FBXL3_LRR-like	<107..182	CDD:480268	14/82 (17%)
		leucine-rich repeat	125..151	CDD:275381	5/26 (19%)
		leucine-rich repeat	152..177	CDD:275381	3/24 (13%)
		AMN1	<175..>304	CDD:187754	44/166 (27%)
		leucine-rich repeat	178..203	CDD:275381	10/32 (31%)
		leucine-rich repeat	204..230	CDD:275381	8/25 (32%)
		leucine-rich repeat	231..256	CDD:275381	7/26 (27%)
		leucine-rich repeat	257..281	CDD:275381	8/50 (16%)