Protein Alignment CG14891 and Lrrc29

DIOPT Version :10

• Sequence 1: NP_650560.1
• Gene: CG14891 / 42013
• FlyBaseID: FBgn0038445
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_006255593.1
• Gene: Lrrc29 / 502201
• RGDID: 1593150
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 109/515 - (21%)
• Similarity: 172/515 - (33%)
• Gaps: 163/515 - (31%)

  Fly    26 VRQLTISGSRRFLKYQLLKYFSIFGKVEKLHWKKKKRSGSVLFYEATHAAKALYCTKHTIDGHDL 90
            :|.|.::|.|...........|.|..:|:|                    ...||        .|
  Rat   207 LRDLNLAGLRDLTDLSFNHLSSCFPSLERL--------------------SLAYC--------HL 243

  Fly    91 YLQASTSWHPTP------------------VEESGTLSAYDLPITDDIWWKVLDYLSLNERLNFA 137
            ..:..::|..|.                  .|.:|||.|.||..|                   .
  Rat   244 TFELGSTWGSTSPQASSPSQLSFHNLLQFIKERAGTLRALDLSGT-------------------G 289

  Fly   138 ASCERFQAIYELDSHRINHVLNMKDVCTLTHRVIKRLMLLSGKHIHCVTGGPLHPNWPYLTEFVQ 202
            ...|..||        :..|..:|         ::.|.|.|.|.:.......|....|.||. :.
  Rat   290 LPPEALQA--------LGQVTGLK---------LEELNLNSCKDLSSEAVATLCRQQPGLTS-LD 336

  Fly   203 LLGVSCPNLTELSFFKISVSLAHMTHLFDGANGLINITNISLRRC-NLKDAHIYCLQMLSKLKSL 266
            |.|  |..||:.:...:|..|.|:.||             ||::. .|.||....|..|.:|:||
  Rat   337 LSG--CSELTDRALLAVSRGLHHLRHL-------------SLKKLQRLTDAGCIALGALHELQSL 386

  Fly   267 DIRENFSIKGDSLKSLPISLEILNVSGCVDLSPKCLIQLAALSHLRELRCPGIVKFAKDNELYGR 331
            |:.|...:.|         .|:..|.|.|..:|      .||:.||...|..:    ||..:...
  Rat   387 DMAECCLVSG---------RELAQVLGSVRRAP------PALTSLRLAYCSSL----KDASVLSM 432

  Fly   332 LAHYCPMLEVLELTDFMNVIQLGGLSRLHTLVIHSSA---------------------------- 368
            :....|.|:||:|:..: .:....:..:.|.:||.|.
  Rat   433 IPALGPSLKVLDLSSCV-ALTNQTMQAICTYLIHLSVLRLAWCKELQDWGLLGLKEPSDEPVLNP 496

  Fly   369 QLDYHVNNVLL-----------TSIAESYSLRHLEILDSFGPMSDTSFDLSI-FSQLKELRTLIL 421
            ||...|.|...           :|:....:|:.|: |.:...::|.|....: |.||::|...:|
  Rat   497 QLHQEVENQAPDHQEPSSEPQGSSLLMLQALQELD-LTACSKLTDASLAKVLQFPQLRQLSLSLL 560

  Fly   422 HNQNFTTLHLMGLQK-LSTLEFLDLSGSPNLSNEVVAKLTKSLSGLRRLKVDFCPLITRQ 480
              ..||.:.|:.:.: ..:||.|.||...:||:|...:..:....|:.|.:..|..:|.|
  Rat   561 --PAFTDMGLVAVARGCPSLERLTLSHCSHLSDEGWVQAARLWPRLQHLNLSSCSQVTEQ 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14891	NP_650560.1	RRM	41..92	CDD:214636	7/50 (14%)
		leucine-rich repeat	211..237	CDD:275381	7/25 (28%)
		LRR	<235..>463	CDD:443914	60/269 (22%)
		leucine-rich repeat	239..262	CDD:275381	7/23 (30%)
		leucine-rich repeat	263..285	CDD:275381	6/21 (29%)
		leucine-rich repeat	286..338	CDD:275381	12/51 (24%)
		leucine-rich repeat	339..387	CDD:275381	13/86 (15%)
		leucine-rich repeat	388..415	CDD:275381	8/27 (30%)
		leucine-rich repeat	416..439	CDD:275381	5/23 (22%)
		leucine-rich repeat	440..465	CDD:275381	8/24 (33%)
Lrrc29	XP_006255593.1	leucine-rich repeat	124..142	CDD:275381
		PPP1R42	<170..410	CDD:455733	61/291 (21%)
		leucine-rich repeat	173..206	CDD:275381
		leucine-rich repeat	207..232	CDD:275381	6/24 (25%)
		leucine-rich repeat	233..279	CDD:275381	8/73 (11%)
		leucine-rich repeat	280..300	CDD:275381	8/46 (17%)
		AMN1	292..480	CDD:187754	57/240 (24%)
		leucine-rich repeat	306..331	CDD:275381	5/24 (21%)
		leucine-rich repeat	332..357	CDD:275381	9/27 (33%)
		leucine-rich repeat	358..439	CDD:275381	27/112 (24%)
		leucine-rich repeat	383..408	CDD:275381	10/33 (30%)
		leucine-rich repeat	413..437	CDD:275381	6/27 (22%)
		leucine-rich repeat	440..465	CDD:275381	5/25 (20%)
		leucine-rich repeat	466..526	CDD:275381	6/59 (10%)
		leucine-rich repeat	527..577	CDD:275381	13/52 (25%)
		AMN1	<564..>638	CDD:187754	15/55 (27%)
		leucine-rich repeat	578..603	CDD:275381	8/24 (33%)
		leucine-rich repeat	604..629	CDD:275381	5/15 (33%)
		leucine-rich repeat	630..655	CDD:275381