Protein Alignment CG14891 and Fbxl2

DIOPT Version :10

• Sequence 1: NP_650560.1
• Gene: CG14891 / 42013
• FlyBaseID: FBgn0038445
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_038938600.1
• Gene: Fbxl2 / 363156
• RGDID: 1562243
• Length: 439
• Species: Rattus norvegicus
• Alignment Length: 275
• Identity: 71/275 - (25%)
• Similarity: 120/275 - (43%)
• Gaps: 42/275 - (15%)

  Fly   238 NITNISLRRC-NLKDAHIYCL-QMLSKLKSLDIRENFSIKGDSLKSLP---ISLEILNVSGCVDL 297
            ||.:::|..| .:.|:..|.| :..||||.||:....|:...|||.:.   .:||.||:|.|..:
  Rat   121 NIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSVTNSSLKGISEGCRNLEYLNLSWCDQI 185

  Fly   298 SPKCLIQLA-ALSHLRELRCPGIVKFAKDNELYGRLAHYCPMLEVLEL------TDFMNVIQL-G 354
            :.:.:..|. ....|:.|...|..:.  ::|....:.::|..|..|.|      || ..|:|: .
  Rat   186 TKEGIEALVRGCRGLKALLLRGCTQL--EDEALKHIQNHCHELVSLNLQSCSRITD-DGVVQICR 247

  Fly   355 GLSRLHTLVIHSSAQLDYHVNNVLLTSIAESYSLRHLEILDS--FGPMSDTSFDLSIFSQLKELR 417
            |..||..|.:...:.|    .:..||::  ..:...|::|::  ...::|..|.| :.....:|.
  Rat   248 GCHRLQALCLSGCSNL----TDASLTAL--GLNCPRLQVLEAARCSHLTDAGFTL-LARNCHDLE 305

  Fly   418 TLILHNQNFTT--------LHLMGLQKLSTLEFLDLSGSPNLSNEVVAKLTKSLSG---LRRLKV 471
            .:.|......|        :|...||.||      ||....:::|.:..|:.|..|   ||.|::
  Rat   306 KMDLEECVLITDSTLIQLSIHCPKLQALS------LSHCELITDEGILHLSSSTCGHERLRVLEL 364

  Fly   472 DFCPLITRQLTKILE 486
            |.|.|:|....:.||
  Rat   365 DNCLLVTDASLEHLE 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14891	NP_650560.1	RRM	41..92	CDD:214636
		leucine-rich repeat	211..237	CDD:275381
		LRR	<235..>463	CDD:443914	60/247 (24%)
		leucine-rich repeat	239..262	CDD:275381	6/24 (25%)
		leucine-rich repeat	263..285	CDD:275381	8/24 (33%)
		leucine-rich repeat	286..338	CDD:275381	12/52 (23%)
		leucine-rich repeat	339..387	CDD:275381	14/54 (26%)
		leucine-rich repeat	388..415	CDD:275381	5/28 (18%)
		leucine-rich repeat	416..439	CDD:275381	7/30 (23%)
		leucine-rich repeat	440..465	CDD:275381	5/24 (21%)
Fbxl2	XP_038938600.1	F-box_SF	<38..69	CDD:459239
		leucine-rich repeat	68..95	CDD:275381
		AMN1	<92..239	CDD:187754	32/119 (27%)
		leucine-rich repeat	96..115	CDD:275381
		leucine-rich repeat	122..147	CDD:275381	6/24 (25%)
		leucine-rich repeat	148..173	CDD:275381	8/24 (33%)
		leucine-rich repeat	174..199	CDD:275381	7/24 (29%)
		AMN1	184..383	CDD:187754	48/212 (23%)
		leucine-rich repeat	200..225	CDD:275381	5/26 (19%)
		leucine-rich repeat	226..251	CDD:275381	8/25 (32%)
		leucine-rich repeat	252..277	CDD:275381	5/30 (17%)
		leucine-rich repeat	278..303	CDD:275381	5/25 (20%)
		leucine-rich repeat	304..329	CDD:275381	4/24 (17%)
		leucine-rich repeat	330..352	CDD:275381	8/27 (30%)
		leucine-rich repeat	359..378	CDD:275381	7/18 (39%)
		leucine-rich repeat	384..409	CDD:275381