Protein Alignment CG14891 and Fbxl4

DIOPT Version :10

• Sequence 1: NP_650560.1
• Gene: CG14891 / 42013
• FlyBaseID: FBgn0038445
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_572951.1
• Gene: Fbxl4 / 32378
• FlyBaseID: FBgn0030555
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 115/546 - (21%)
• Similarity: 186/546 - (34%)
• Gaps: 167/546 - (30%)

  Fly    10 NFYIE--------RGVAYTEDREVVRQLT-------------------------ISGSRRFLKYQ 41
            |:|.|        |.|..|::....:|:|                         ||...|.||:|
  Fly   223 NYYTEIDAIMLCGRTVTKTQNLLAKQQITQHSRTLVSPPPDAIGSTSGDGSGGSISHKLRTLKFQ 287

  Fly    42 LLKYFSIFGKVEKLHWKKKKRSGSVLFYEATHAAKALYCTKHTIDGHDLYLQASTSWHPTPVEES 106
                            ......|:...:|..:...:.:...:.:||.....|
  Fly   288 ----------------PNCGEDGATKLHEFINNDLSQFLADNCVDGEAAAPQ------------- 323

  Fly   107 GTLSAYDLPITDDIWWKVLDYLSLNERLNFAASCERFQAIYELDSHRINH----------VLNMK 161
              :...|||.  :|..::|.||.|............|   |::..|.:.:          |.:.:
  Fly   324 --ICLTDLPF--EILLRILSYLDLKSLFRVGHVSRTF---YDISRHPLLYAEISLKPYWDVASSE 381

  Fly   162 DVCTLTHR--VIKRLMLLSGKHIHCVTGGPLHPNWPYLTEFVQLLGVSCPNLTELSF----FKIS 220
            .:|||..|  ::::|.|     ..|...|.:.|     |||.:.|.....|||.|..    |..:
  Fly   382 LLCTLARRATMLRKLDL-----SWCGGFGNVSP-----TEFKKFLTQRGDNLTHLRLNSCKFLNA 436

  Fly   221 VSLAHMTHLFDGANGLINITNISLRRCNLKD--AHIYCLQMLSKLKSLDIRENFSIKGDSLKSLP 283
            ..:.::..:.|      |:..:|||.|..:.  .:..||..|..|:.||:.:.:
  Fly   437 SCIENVGIVCD------NLIELSLRNCATEPPLLNFSCLANLKNLERLDLFQTY----------- 484

  Fly   284 ISLEILNVSGCVDLSPKCLIQLAA---LSHLRELRCPGIVKFAKDNELYGRLAHYCPMLEVLEL- 344
            ...|:|            |..|..   |.||....|.  |....|| :...||.|...|..|:|
  Fly   485 FETELL------------LSMLEGNRKLKHLNLAFCG--VSVNMDN-VAAHLATYNTQLISLDLW 534

  Fly   345 -TDFMNVIQLGGLSRLHTLVIHSSAQLDYHVNNVLLTSIAESYSLRHLEILDSFGPMSDTSFDLS 408
             ..|::...|..|:|||.|     .:||.            .:.:|...:.|..         ..
  Fly   535 KAHFLSSRGLQSLARLHQL-----EELDL------------GWCMREASLGDGL---------FQ 573

  Fly   409 IFSQLKELRTLILHNQNFTT----LHLMGLQKLSTLEFLDLSGSPNLSNEVVAKLTKSLSGLRRL 469
            :.|...:|:.|.|.....||    :|:..|.|  .||.|||.|..|:::|.|..:..:...|:.|
  Fly   574 LLSNCPKLKKLFLSAVRGTTERDLMHIAALGK--NLEQLDLMGILNITHERVYDILVNCPKLQLL 636

  Fly   470 KVDFCP-LITRQLTKILEGNPKLQVD 494
            .:.||. ::.|....:.|.:.:.:||
  Fly   637 DLSFCDNIMDRDFDLLAEWSRQFKVD 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14891	NP_650560.1	RRM	41..92	CDD:214636	5/50 (10%)
		leucine-rich repeat	211..237	CDD:275381	5/29 (17%)
		LRR	<235..>463	CDD:443914	57/238 (24%)
		leucine-rich repeat	239..262	CDD:275381	7/24 (29%)
		leucine-rich repeat	263..285	CDD:275381	3/21 (14%)
		leucine-rich repeat	286..338	CDD:275381	14/54 (26%)
		leucine-rich repeat	339..387	CDD:275381	12/49 (24%)
		leucine-rich repeat	388..415	CDD:275381	3/26 (12%)
		leucine-rich repeat	416..439	CDD:275381	8/26 (31%)
		leucine-rich repeat	440..465	CDD:275381	9/24 (38%)
Fbxl4	NP_572951.1	F-box-like	326..370	CDD:463757	11/48 (23%)
		leucine-rich repeat	393..422	CDD:275381	9/38 (24%)
		leucine-rich repeat	423..442	CDD:275381	4/18 (22%)
		LRR	<427..>639	CDD:443914	61/271 (23%)
		leucine-rich repeat	449..474	CDD:275381	7/24 (29%)
		leucine-rich repeat	475..499	CDD:275381	7/46 (15%)
		leucine-rich repeat	500..527	CDD:275381	10/29 (34%)
		leucine-rich repeat	528..552	CDD:275381	8/23 (35%)
		leucine-rich repeat	553..580	CDD:275381	6/52 (12%)
		leucine-rich repeat	581..606	CDD:275381	8/26 (31%)
		leucine-rich repeat	607..632	CDD:275381	9/24 (38%)
		leucine-rich repeat	633..652	CDD:275381	5/18 (28%)