Protein Alignment CG14891 and Fbxl18

DIOPT Version :10

• Sequence 1: NP_650560.1
• Gene: CG14891 / 42013
• FlyBaseID: FBgn0038445
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001028484.2
• Gene: Fbxl18 / 231863
• MGIID: 2444450
• Length: 707
• Species: Mus musculus
• Alignment Length: 439
• Identity: 95/439 - (21%)
• Similarity: 172/439 - (39%)
• Gaps: 106/439 - (24%)

  Fly   104 EESGTLSAYD---LPITDDIWWKVLDYL-SLNERLNFAASCERFQAIYELDSHRINHVLNMKDVC 164
            ||:...:|.|   |..:|:|...:|.:: |.:..|:...:|.:..|:. ||...::.||..||.
Mouse     5 EEAAAEAAGDTHLLGFSDEILLHILSHVPSTDLVLSVRRTCRKLAALC-LDKSLVHTVLLQKDY- 67

  Fly   165 TLTHRVIKRLMLLSGKHI--------HCVTGGPLHPNWPYLTEFVQLLGVS---CPNLTELSFFK 218
            ..:...:|:|:...|:.|        :.::|..:.    ::.....|:.|:   | :||.|...|
Mouse    68 QASEEKVKQLVKEIGREIQQLNMAGCYWLSGSTIE----HVARCHSLVKVNLSGC-HLTSLRLSK 127

  Fly   219 ISVSLAHMTHL-------FDGANGLINITNISLRRCNLKDAHIYCLQMLSKLKSLDIRENFSIKG 276
            :..:|.|:..|       || |:.|.:....:|.|             :.:||......::.:..
Mouse   128 VLSALQHLRSLAIDVSPGFD-ASQLSSECKATLSR-------------VQELKQTLFTPSYGVVP 178

  Fly   277 --DSLKSLPISLEILNVS--GCVDLSPKCLIQLAALSHLRELRCPGIVKFAKDNELYGRLAHYCP 337
              .||:.|.:..|||:.:  |.| ||.:.::..:.:.|.:.||.           .|.|||....
Mouse   179 CCASLQKLLLYFEILDRTREGAV-LSGQLMVGQSNVPHYQNLRV-----------FYARLAPGYI 231

  Fly   338 MLEVLELTDFMNVIQLGGLSRLHTLVI-------HSSAQ---LDYHVNNVLLTSIA-------ES 385
            ..||:.|  ::.|:.......||..:|       .|.|.   ||....||.|.::.       .|
Mouse   232 NQEVVRL--YLAVLSDRTPENLHAFLISVPGSFAESGATKNLLDSMARNVALDALQLPKSWLNGS 294

  Fly   386 YSLRHLEILDSFGPMSDTSFDLS---IFSQL----KELRTLILHNQNFTTLHLMGLQKLSTLEFL 443
            ..|:|::..:.| ..|.:...||   :..:|    |:||:|       .:|:|.|.....:.:.|
Mouse   295 TLLQHMKFNNPF-YFSFSRCTLSGGHLIQRLINGGKDLRSL-------ASLNLSGCVHCLSADSL 351

  Fly   444 DLSGSPNLSNEVVAKLTKSLSGLRRLKVD-------------FCPLITR 479
            ......::.:.::..|.:|...|..|.:.             .|.|:.|
Mouse   352 LRKAEDDIDSSILETLVESCCNLHHLNLSAAHHHSSDGLGRHLCQLLAR 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14891	NP_650560.1	RRM	41..92	CDD:214636
		leucine-rich repeat	211..237	CDD:275381	10/32 (31%)
		LRR	<235..>463	CDD:443914	53/255 (21%)
		leucine-rich repeat	239..262	CDD:275381	2/22 (9%)
		leucine-rich repeat	263..285	CDD:275381	5/23 (22%)
		leucine-rich repeat	286..338	CDD:275381	14/53 (26%)
		leucine-rich repeat	339..387	CDD:275381	15/64 (23%)
		leucine-rich repeat	388..415	CDD:275381	7/33 (21%)
		leucine-rich repeat	416..439	CDD:275381	6/22 (27%)
		leucine-rich repeat	440..465	CDD:275381	3/24 (13%)
Fbxl18	NP_001028484.2	F-box_SF	17..60	CDD:459239	10/43 (23%)
		FBXL18_LRR	74..664	CDD:466163	77/368 (21%)
		leucine-rich repeat	85..109	CDD:275381	2/27 (7%)
		leucine-rich repeat	110..131	CDD:275381	7/21 (33%)
		leucine-rich repeat	308..330	CDD:275381	4/21 (19%)
		leucine-rich repeat	331..373	CDD:275381	9/48 (19%)
		leucine-rich repeat	374..403	CDD:275381	5/27 (19%)
		leucine-rich repeat	404..473	CDD:275381
		leucine-rich repeat	522..548	CDD:275381
		leucine-rich repeat	549..578	CDD:275381
		leucine-rich repeat	579..604	CDD:275381
		leucine-rich repeat	605..629	CDD:275381