DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG14891 and skpt-1

DIOPT Version :10

Sequence 1:NP_650560.1 Gene:CG14891 / 42013 FlyBaseID:FBgn0038445 Length:495 Species:Drosophila melanogaster
Sequence 2:NP_741137.1 Gene:skpt-1 / 175749 WormBaseID:WBGene00018613 Length:421 Species:Caenorhabditis elegans


Alignment Length:357 Identity:83/357 - (23%)
Similarity:135/357 - (37%) Gaps:89/357 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   112 YDLPITDDIWWKVLDYLSLNERLNFAASCERFQAIYELDSHRINH--VLNMKD-------VCTLT 167
            |.:|  |:|..::...|...:.|:....|.||..|    .|:..:  :.:.:|       :..|:
 Worm    91 YSIP--DEITEQIFSNLKKKDLLSAMLVCHRFYGI----GHKSRNWIITDAQDRPISEISLIALS 149

  Fly   168 HRVIKRLMLLSGKHIHCVTGGPLHPNWPYLTEFVQLLGVSCPNLTELSFFKISVSLAHMTHLFDG 232
            .|.||.|.|...|....:...      ..|.| |.||..|...|.:||  :.:::...|      
 Worm   150 QRKIKVLRLAGAKADRILRAD------ERLVE-VALLSTSRLELLDLS--RTNLTARQM------ 199

  Fly   233 ANGLINITNISLRRC----------NLKDAHI-YCLQMLSKLKSLDI--RENFSIKGDSL----- 279
                    .|.|:.|          |..|.|: .|:.....|:.|||  ....:..|.||     
 Worm   200 --------QIMLKPCQKLKCLSIEGNQLDDHVAICIAENRGLRELDISMTNGITANGASLIFRNC 256

  Fly   280 KSLPISLEILNVSGCVDLSPKCLIQLAALSH-LRELRCPGIVK-FAKDN---ELYGRLAHYCPML 339
            |    .|:.||::.|....|...:.:.::.. |::|...|.|: |..:|   |:....::|...|
 Worm   257 K----DLQQLNLAWCGLTQPIVTVIIHSIGEKLKKLNLSGTVRNFGINNKHIEILAAKSNYVTDL 317

  Fly   340 EV---LELTDFMNVIQLGGLSRLHTLVIHSSAQLD----YHVNNVLLTSIAESYSLRHLEILDSF 397
            ::   :|::|....:.|....||.|:.::....||    .|.|           |...|..|:..
 Worm   318 DLSDNVEISDPGLAVILNKFPRLTTISLNRCYGLDPNMVVHFN-----------SKPSLVYLNVH 371

  Fly   398 GPMSDTSFD--LSIFSQLKELRTLILHNQNFT 427
            |.:|||:.:  |.:.|.||..|...    |||
 Worm   372 GCVSDTNMELFLEMCSNLKVNRQYF----NFT 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14891NP_650560.1 RRM 41..92 CDD:214636
leucine-rich repeat 211..237 CDD:275381 4/25 (16%)
LRR <235..>463 CDD:443914 54/225 (24%)
leucine-rich repeat 239..262 CDD:275381 7/33 (21%)
leucine-rich repeat 263..285 CDD:275381 8/28 (29%)
leucine-rich repeat 286..338 CDD:275381 13/56 (23%)
leucine-rich repeat 339..387 CDD:275381 11/54 (20%)
leucine-rich repeat 388..415 CDD:275381 9/28 (32%)
leucine-rich repeat 416..439 CDD:275381 4/12 (33%)
leucine-rich repeat 440..465 CDD:275381
skpt-1NP_741137.1 F-box-like 92..130 CDD:463757 10/43 (23%)
leucine-rich repeat 153..183 CDD:275381 10/36 (28%)
RNA1 <171..347 CDD:444072 45/196 (23%)
leucine-rich repeat 184..208 CDD:275381 7/39 (18%)
leucine-rich repeat 209..232 CDD:275381 4/22 (18%)
leucine-rich repeat 233..258 CDD:275381 8/28 (29%)
leucine-rich repeat 259..284 CDD:275381 5/24 (21%)
leucine-rich repeat 285..313 CDD:275381 7/27 (26%)
leucine-rich repeat 314..339 CDD:275381 4/24 (17%)
leucine-rich repeat 340..362 CDD:275381 6/32 (19%)
leucine-rich repeat 365..388 CDD:275381 7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.