Protein Alignment CG14891 and gadr-6

DIOPT Version :10

• Sequence 1: NP_650560.1
• Gene: CG14891 / 42013
• FlyBaseID: FBgn0038445
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_493455.1
• Gene: gadr-6 / 173273
• WormBaseID: WBGene00009823
• Length: 710
• Species: Caenorhabditis elegans
• Alignment Length: 455
• Identity: 96/455 - (21%)
• Similarity: 152/455 - (33%)
• Gaps: 152/455 - (33%)

  Fly    73 HAAKALYCTKHTIDGHDL--YLQASTSWHPTPVEESGTLSAYDLPITDDIWWKVLDYLSLNERLN 135
            |....|:.|.. ||..||  ..|.||:|..|        :...||:...:  .|.....||.  :
 Worm   102 HYMSRLFRTSQ-IDHLDLSGRSQFSTAWLKT--------TGQQLPLLRTL--NVSGVKLLNP--D 153

  Fly   136 FAASCERFQAIYELDSHRINHVLNMKDVCTLTHRVIKRLMLLSGKHIHCVTGGPLHPNWPYLTEF 200
            |...|:.|..:|.||       ::...|..||.  |.||..|.    |......::.:|..:.|
 Worm   154 FFQFCKSFPNLYSLD-------ISNCGVTILTG--ISRLKNLR----HLSLRSLIYESWYDIRE- 204

  Fly   201 VQLLGVSCPNLTELSFFKISVSLAHMTHLFDGANGLINITNISLRRCNLKDAHIYCLQMLSKLKS 265
              |..:...|:.:||.        |.||              ..|| |:: ..:.|.|:|.:|:.
 Worm   205 --LFALKLLNVLDLSM--------HSTH--------------HARR-NMQ-RFLDCKQVLPELRF 243

  Fly   266 LDIRENFSIKGDSLKSLPISLEILNVSGCVDLSPKCLIQLAALSHLRELRCPGI----------V 320
            |:...|. :..|.|:.|.|:...|:....||    |.::....|.:|.|.|...          :
 Worm   244 LECSGNL-MDEDMLEELLITHSHLHQLAIVD----CDVKAPKSSPIRILSCTTFDSSITALKYYL 303

  Fly   321 KFAKDNE--------------LYGRLAHY----CPMLEVLEL----------------------- 344
            ...:.||              |:.|...|    |..|.:..|
 Worm   304 NLKRRNEVQICFQELRLHVKRLHERKMQYDVTECVTLSLQSLEKLPCSLIMNFDIVEERLFTSRL 368

  Fly   345 ---TDFMNVIQLGG---LSRLHTLVIHSSAQLDYHVNNV---LLTSIAESYSLRHLEILDSFGPM 400
               .||:..|.|..   |||:||.:|     .|..:|||   |:..:........:..|
 Worm   369 SFEADFLAEIVLHNFHRLSRVHTRLI-----CDILLNNVNRQLIRDLRAETMWNAIIYL------ 422

  Fly   401 SDTSFDLSIFSQLKELRTLILHNQNFTTLHLMGLQKLSTLEFLDLSGSPNLSNEVVAKLTKSLSG 465
                |::.:|...::|:.:..|..  .:||               :|.|.:..:.:..||..::|
 Worm   423 ----FNMGVFVDKQKLKGIASHCA--ASLH---------------NGDPIIEEQAMRILTSCVTG 466

  Fly   466  465
             Worm   467  466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14891	NP_650560.1	RRM	41..92	CDD:214636	7/20 (35%)
		leucine-rich repeat	211..237	CDD:275381	5/25 (20%)
		LRR	<235..>463	CDD:443914	55/287 (19%)
		leucine-rich repeat	239..262	CDD:275381	6/22 (27%)
		leucine-rich repeat	263..285	CDD:275381	6/21 (29%)
		leucine-rich repeat	286..338	CDD:275381	14/79 (18%)
		leucine-rich repeat	339..387	CDD:275381	17/79 (22%)
		leucine-rich repeat	388..415	CDD:275381	3/26 (12%)
		leucine-rich repeat	416..439	CDD:275381	4/22 (18%)
		leucine-rich repeat	440..465	CDD:275381	4/24 (17%)
gadr-6	NP_493455.1	LRR	<85..>217	CDD:443914	35/143 (24%)
		leucine-rich repeat	86..112	CDD:275381	3/9 (33%)
		leucine-rich repeat	113..138	CDD:275381	10/32 (31%)
		leucine-rich repeat	139..163	CDD:275381	6/27 (22%)
		leucine-rich repeat	164..185	CDD:275381	9/29 (31%)