DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Decay and CASP7

DIOPT Version :9

Sequence 1:	NP_477462.1	Gene:	Decay / 42008	FlyBaseID:	FBgn0028381	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001253986.1	Gene:	CASP7 / 840	HGNCID:	1508	Length:	388	Species:	Homo sapiens

Alignment Length:	257	Identity:	90/257 - (35%)
Similarity:	145/257 - (56%)	Gaps:	22/257 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 TYE---NCARAGIALILNHKD---VKGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEIND 106
            ||:   |..:.|..:|:|:|:   |.|...|.||::|.:.:....:..||||..::|.:.:::.|
Human   142 TYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQD 206

  Fly   107 TLKEVAREDHSQNDCFVLAVMSHGTEGKVYAKDMSYPVERLWNPFLGDNCKTLKNKPKLFFIQAC 171
            .||:.:.|||:...||...::|||.|..:|.||...|::.|...|.||.||||..||||||||||
Human   207 LLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQAC 271

  Fly   172 RGANLEKAVEFSSFAVMTRELVPEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFI 236
            ||..|:..::..|..:...:..|.         |.||..||.|..|||...::|:|:...||||:
Human   272 RGTELDDGIQADSGPINDTDANPR---------YKIPVEADFLFAYSTVPGYYSWRSPGRGSWFV 327

  Fly   237 QSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMSTLTK 298
            |:||.:|::..       :.:|::::||.||.:||..::|.:.:...::.|::|..:|.|||
Human   328 QALCSILEEHG-------KDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTK 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	87/248 (35%)
CASP7	NP_001253986.1	CASc	145..386	CDD:237997	88/254 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920