Protein Alignment Decay and CASP3

DIOPT Version :10

• Sequence 1: NP_477462.1
• Gene: Decay / 42008
• FlyBaseID: FBgn0028381
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_004337.2
• Gene: CASP3 / 836
• HGNCID: 1504
• Length: 277
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 103/302 - (34%)
• Similarity: 167/302 - (55%)
• Gaps: 35/302 - (11%)

  Fly     1 MDDTDFSLFGQKNKHKKDKADATKIAHTPTSELDLKRIIISRPTNEDTYE-NCARAGIALILNHK 64
            |::|:.|:..:..|:.:     .||.|...| :|      |..:.:::|: :....|:.:|:|:|
Human     1 MENTENSVDSKSIKNLE-----PKIIHGSES-MD------SGISLDNSYKMDYPEMGLCIIINNK 53

  Fly    65 DV---KGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVAREDHSQNDCFVLAV 126
            :.   .|...|.||:.|..::..|.:...::||..:|||..||.:.:::|::||||:...||..:
Human    54 NFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVL 118

  Fly   127 MSHGTEGKVYAKDMSYPVERLWNPFLGDNCKTLKNKPKLFFIQACRGANLEKAVEFSSFAVMTRE 191
            :|||.||.::..:....::::.|.|.||.|::|..|||||.||||||..|:..:|       |..
Human   119 LSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIE-------TDS 176

  Fly   192 LVPEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFIQSLCRVLDQAAANEAATPEG 256
            .|.:..|.     :.||..||.|..|||...::|:||..||||||||||.:|.|.|       :.
Human   177 GVDDDMAC-----HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYA-------DK 229

  Fly   257 VELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMSTLTK 298
            :|.:.:||.||||||.|::|.:.:...:..|::|..:|.|||
Human   230 LEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTK 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	92/248 (37%)
CASP3	NP_004337.2	CASc	37..277	CDD:214521	93/254 (37%)