DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Decay and caspbl

DIOPT Version :9

Sequence 1:	NP_477462.1	Gene:	Decay / 42008	FlyBaseID:	FBgn0028381	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001139064.1	Gene:	caspbl / 566185	ZFINID:	ZDB-GENE-090311-53	Length:	409	Species:	Danio rerio

Alignment Length:	320	Identity:	86/320 - (26%)
Similarity:	128/320 - (40%)	Gaps:	78/320 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DDTDFSL-FGQKNKHKKDKADATKIAHTPTSELDLKRIIISRPTNEDTYENCARAGIALIL-NHK 64
            ||...|: |.::|         |...:||.|...                   |.|:||:: |..
Zfish   145 DDASISIHFYKQN---------TLSIYTPVSRTQ-------------------RKGLALLITNIL 181

  Fly    65 DVKGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVA-REDHSQNDCFVLAVMS 128
            ....|..|.|.|||.::||..|:...|.|..:.:||.:||:..:::.: |.:|...|...:.:||
Zfish   182 FANKQDDRAGAERDEENMEWLLKNLNFMVIKYRNLTGNEISRAVQDFSRRHEHQDADSTFVVIMS 246

  Fly   129 HGTEGKVYAKDMSYPVERLWNP------FLGD--------NCKTLKNKPKLFFIQACRGANLEKA 179
            ||  .::..||....|...|..      |:.|        ||..|.:|||:..||||||..|.
Zfish   247 HG--DRIQNKDAILGVNYNWLQNRNDVYFVEDTFSHLNSVNCPALIDKPKVILIQACRGGQLG-- 307

  Fly   180 VEFSSFAVMTRELVPEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFIQSLCRVLD 244
                  .|..::.|||..:.|.       ...|.:.|.||.....::|:...||:||..:..|..
Zfish   308 ------GVPVKDCVPESDSWVH-------KEKDFVCFMSTMPDVVAYRDEVKGSYFISYIVDVFC 359

  Fly   245 QAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEAL-NQMKEMPNFMST-LTKTFQL 302
            .:|..:       .::.|.    ||||...:   |:|.. .|.|.:|....| |.|.|.|
Zfish   360 SSACKD-------HIMELF----RKVAARME---KDERFRRQAKLLPCIERTSLVKKFYL 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	76/265 (29%)
caspbl	NP_001139064.1	Pyrin_ASC-like	5..84	CDD:260033
caspbl	NP_001139064.1	CASc	167..406	CDD:237997	77/289 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587237
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840