DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Decay and casp2

DIOPT Version :9

Sequence 1:	NP_477462.1	Gene:	Decay / 42008	FlyBaseID:	FBgn0028381	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	XP_005157976.1	Gene:	casp2 / 373118	ZFINID:	ZDB-GENE-030825-3	Length:	437	Species:	Danio rerio

Alignment Length:	350	Identity:	91/350 - (26%)
Similarity:	136/350 - (38%)	Gaps:	82/350 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KKDKADATKIAHTPTSELDLKRIIISRPTNEDTYENCARA------------------------- 55
            :|||..:......||.|....   ..||...::.|.|..|
Zfish    99 EKDKCFSEPSLSLPTQECVTP---AKRPRTHESMEMCLDADSPVTTAVLPCTPEFYQSHRPQAYP 160

  Fly    56 ------GIALILNH---------KDVKGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEIN 105
                  |:||:|::         .|:     |.|.|.|.:.:........|.|....|||...:.
Zfish   161 MRSCPRGLALVLSNVRFDSANTDLDI-----RRGGEVDEETLRRLFTELDFKVSLHRDLTAEAMR 220

  Fly   106 DTLKEVA-REDHSQNDCFVLAVMSHGTEGKVYAKDMSYPVERLWNPFLGDN--CKTLKNKPKLFF 167
            ..|::.| :::|:..||.|:.::|||.||.||..| ...:|..|...:.||  |..|:||||:||
Zfish   221 RCLEQFAQQQEHAAYDCAVVCLLSHGVEGSVYGTD-GQLLELDWVFEVFDNARCPLLQNKPKMFF 284

  Fly   168 IQACRGANLEKAVEFSSFAVMT------------------RELVPEPAAAVQPITYAIPSTADIL 214
            ||||||..::..|:.......|                  ||...|...  :.:...:|..:|::
Zfish   285 IQACRGEEMDNGVDQLDGQERTQSPGCEQRDAGREGERDNREKKEEKER--ERLRVKLPQRSDMI 347

  Fly   215 VFYSTFDKF--FSFRNVDDGSWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSN 277
            ..::|...|  .:.||...||||||.|...:.|.|.|       ..|..:|..||.::. ..:..
Zfish   348 CGFATLKGFSTAAMRNTKKGSWFIQELNTAIRQRANN-------THLSDILVQVNGQIK-SREGY 404

  Fly   278 TKNEALNQMKEMPNFMSTLTKTFQL 302
            ....|.::.|||..|.|:|.|...|
Zfish   405 APGSAHHRCKEMSEFTSSLCKDLYL 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	80/310 (26%)
casp2	XP_005157976.1	CARD_CASP2	7..94	CDD:260040
casp2	XP_005157976.1	CASc	158..430	CDD:237997	79/287 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587225
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740