Protein Alignment Decay and PYCARD

DIOPT Version :9

• Sequence 1: NP_477462.1
• Gene: Decay / 42008
• FlyBaseID: FBgn0028381
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_037390.2
• Gene: PYCARD / 29108
• HGNCID: 16608
• Length: 195
• Species: Homo sapiens
• Alignment Length: 151
• Identity: 36/151 - (23%)
• Similarity: 56/151 - (37%)
• Gaps: 37/151 - (24%)

  Fly    80 DDMEATLQGFGFDVRTFD-DLTFSEINDT-LKEVAREDHSQNDCFVLAVMSHGTEGKVYAKDMSY 142
            |.::.|.:...|.:.|:. :||.:.:.|. |:|:|.:         |...:|...|...|...:.
Human    48 DALDLTDKLVSFYLETYGAELTANVLRDMGLQEMAGQ---------LQAATHQGSGAAPAGIQAP 103

  Fly   143 PVERLWNPFLGDNCKTLKNKPKLFFIQACRGANLEKA--VEFSSFAVMTRELVPEPAAAVQPITY 205
            |....              ||.|.||...|.|.:.:.  ||:...|:..:.|..|...||:
Human   104 PQSAA--------------KPGLHFIDQHRAALIARVTNVEWLLDALYGKVLTDEQYQAVR---- 150

  Fly   206 AIPSTADILVFYSTFDKFFSF 226
            |.|:..      |...|.|||
Human   151 AEPTNP------SKMRKLFSF 165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	36/151 (24%)
PYCARD	NP_037390.2	Pyrin_ASC-like	5..86	CDD:260033	10/46 (22%)
		CARD_ASC_NALP1	113..193	CDD:260039	18/63 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152739
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930