Protein Alignment Decay and CASP14

DIOPT Version :9

• Sequence 1: NP_477462.1
• Gene: Decay / 42008
• FlyBaseID: FBgn0028381
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_036246.1
• Gene: CASP14 / 23581
• HGNCID: 1502
• Length: 242
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 77/268 - (28%)
• Similarity: 119/268 - (44%)
• Gaps: 36/268 - (13%)

  Fly    42 RPTNEDTYENCARAGIALILNHKDVKGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEIND 106
            |...|:.|: .:.|.:||||     ...|.|.|:|.|.|.:|...:...|:.....|.|..:..:
Human     5 RSLEEEKYD-MSGARLALIL-----CVTKAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQE 63

  Fly   107 TLKEVAREDHSQND---CFVLAVMSHGTEGKVYAKD-MSYPVERLWNPFLGDNCKTLKNKPKLFF 167
            .|::..:...|:.|   |..:.:|:||.||.:..:| ....:|.|:......||:.|:.|||::.
Human    64 ELEKFQQAIDSREDPVSCAFVVLMAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYI 128

  Fly   168 IQACRGANLEKAVEFSSFAVMTRELV--PEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVD 230
            ||||||...:..           |.|  .|....::.....||:..|.|..|||.:.:.::|:..
Human   129 IQACRGEQRDPG-----------ETVGGDEIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQ 182

  Fly   231 DGSWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMST 295
            .||.|||:|..|.         |.....:|.|||.|.|::| |.:...:.:|   .|..|...||
Human   183 KGSCFIQTLVDVF---------TKRKGHILELLTEVTRRMA-EAELVQEGKA---RKTNPEIQST 234

  Fly   296 LTKTFQLR 303
            |.|...|:
Human   235 LRKRLYLQ 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	73/253 (29%)
CASP14	NP_036246.1	CASc	18..242	CDD:237997	72/252 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152747
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840