DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Decay and csp-2

DIOPT Version :9

Sequence 1:	NP_477462.1	Gene:	Decay / 42008	FlyBaseID:	FBgn0028381	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001370851.1	Gene:	csp-2 / 177391	WormBaseID:	WBGene00000820	Length:	826	Species:	Caenorhabditis elegans

Alignment Length:	269	Identity:	76/269 - (28%)
Similarity:	132/269 - (49%)	Gaps:	23/269 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 DLKRIIISRPTNEDTYENCARAGIALILNHKDVKGQKQRVGTERDRDDMEATLQGFGFDVRTFDD 98
            |.|:|..:|....:....|.    |:|:|:....|.::|:|:::|:..:....:..|:...::|:
Worm   571 DGKKIDETRKYRNNRSSKCR----AIIINNVVFCGMEKRIGSDKDKKKLSKLFERLGYQSTSYDN 631

  Fly    99 LTFSEINDTLKEVAREDHSQNDCFVLAVMSHGTEGKVYAKDMSYPVERLWNPFLGDNC-KTLKNK 162
            |..|||.:|:::..:.:|  .|..::.:||||.:|.:|..| ..||:.|  ..:...| .:|..|
Worm   632 LKSSEILETVRQFTQSNH--GDSLIITIMSHGDQGLLYGVD-GVPVQML--DIIDLMCTASLAKK 691

  Fly   163 PKLFFIQACRGANLEKAVEFSSFAVMTRELVPEPAAAVQ---PITYAIPSTADILVFYSTFDKFF 224
            ||......|||..:::||....|.....:..|:....::   |......|.||:||.:||...|.
Worm   692 PKWLMCVCCRGDRIDRAVRCDGFIDNFFDRFPKFFQFMKSKFPSHQTSSSQADLLVSFSTSPGFL 756

  Fly   225 SFRNVDDGSWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEM 289
            |||:...|:|:||.|.||:.:.|       :...|..||...||:|..:|::   ::.:...|:.
Worm   757 SFRDETKGTWYIQELYRVIIENA-------KDTHLADLLMETNRRVVEKYEA---DKVVIVCKQA 811

  Fly   290 PNFMSTLTK 298
            |.|.|..||
Worm   812 PEFWSRFTK 820

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	71/249 (29%)
csp-2	NP_001370851.1	pneumo_PspA	239..>533	CDD:411490
		PHA03418	<475..>563	CDD:177646
		CASc	581..824	CDD:237997	72/259 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48030
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm4766
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850