DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Decay and csp-1

DIOPT Version :9

Sequence 1:	NP_477462.1	Gene:	Decay / 42008	FlyBaseID:	FBgn0028381	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001022452.1	Gene:	csp-1 / 175007	WormBaseID:	WBGene00000819	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	305	Identity:	80/305 - (26%)
Similarity:	141/305 - (46%)	Gaps:	40/305 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DTDFSLFGQKNKHKKDKADATKIAHTPTSELDLKRIIISRPTNEDTYE-NCARAGIALILNHKDV 66
            |..:||....::.:..:.||.|..|                .::..|| |....|..|||::::.
Worm   255 DCSYSLEEYDSQSRMPRTDAKKSNH----------------KHKYCYEMNSNPRGTVLILSNENF 303

  Fly    67 KGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVAREDHSQNDCFVLAVMSHGT 131
            |..::||||::|..::....|...:.|....:|....:.:.:||.|...|:  |..:|.::|||.
Worm   304 KNMERRVGTKQDEVNLTKLFQKLQYTVICKRNLEAESMLEAIKEFAEMAHT--DSIILFLLSHGD 366

  Fly   132 -EGKVYAKDMSYPVERL-WNPFLGDNCKTLKNKPKLFFIQACRGANLEKAVEFSSFAVMTRELVP 194
             .|.|:..| ..||..: .:.:|..: :.|..|||...:.||||..|...|.......:..:..|
Worm   367 GAGSVFGID-DMPVNVMEVSTYLAYH-QNLLLKPKWVAVSACRGGKLNMGVPVDGLPALEDKCAP 429

  Fly   195 EP------AAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFIQSLCRVLDQAAANEAAT 253
            ..      .:.:.|.|:. ...||:::.:||.|.|.|:|:.:.|:|:|:|:|:|.::.:
Worm   430 ISKFWNLMMSRIMPGTFT-SLNADVIISFSTTDGFTSYRDEEAGTWYIKSMCKVFNKHS------ 487

  Fly   254 PEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMSTLTK 298
             :.:.||.:||...|.|..:|::...|..|   |:.|..:|.|||
Worm   488 -KTMHLLDILTETGRNVVTKYENVQGNVVL---KQAPEILSRLTK 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	70/253 (28%)
csp-1	NP_001022452.1	SPK	76..188	CDD:214732
csp-1	NP_001022452.1	CASc	285..533	CDD:214521	73/259 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162602
Domainoid	1	1.000	130	1.000	Domainoid score	I3239
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm4766
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.950