Protein Alignment Decay and Casp8

DIOPT Version :9

• Sequence 1: NP_477462.1
• Gene: Decay / 42008
• FlyBaseID: FBgn0028381
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_001264855.1
• Gene: Casp8 / 12370
• MGIID: 1261423
• Length: 500
• Species: Mus musculus
• Alignment Length: 334
• Identity: 95/334 - (28%)
• Similarity: 160/334 - (47%)
• Gaps: 53/334 - (15%)

  Fly     2 DDTDFSLFGQKNKHKKDKAD-------ATKIAHTPTSELDLKRI-IISRPTNEDT---------- 48
            |..:.||.|:...:::...:       ..::..:...|:.||.. :...|..:|:
Mouse   185 DQVNKSLLGKIEDYERSSTERRMSLEGREELPPSVLDEMSLKMAELCDSPREQDSESRTSDKVYQ 249

  Fly    49 YENCARAGIALILNHKD----------VKGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSE 103
            .:|..| |..||:|:.|          ::..|.|.||:.|::.:..|.:...|::.::||.|.:|
Mouse   250 MKNKPR-GYCLIINNHDFSKAREDITQLRKMKDRKGTDCDKEALSKTFKELHFEIVSYDDCTANE 313

  Fly   104 INDTLKEVAREDHSQNDCFVLAVMSHGTEGKVYAKD-MSYPVERLWNPFLGDNCKTLKNKPKLFF 167
            |::.|:.....||...|||:..::|||.:|.||..| ....:..|.:.|.|..|.:|..|||:||
Mouse   314 IHEILEGYQSADHKNKDCFICCILSHGDKGVVYGTDGKEASIYDLTSYFTGSKCPSLSGKPKIFF 378

  Fly   168 IQACRGANLEKAV-EFSSFAVMTRELVPEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDD 231
            ||||:|:|.:|.| :.:.|......|..:.::...    .||..||.|:..:|.....|:|:..:
Mouse   379 IQACQGSNFQKGVPDEAGFEQQNHTLEVDSSSHKN----YIPDEADFLLGMATVKNCVSYRDPVN 439

  Fly   232 GSWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMSTL 296
            |:|:|||||:.|.:..      |:|.::|.:||.||      |..:.|::..|:.|:||.
Mouse   440 GTWYIQSLCQSLRERC------PQGDDILSILTGVN------YDVSNKDDRRNKGKQMPQ----- 487

  Fly   297 TKTFQLRVK 305
             .||.||.|
Mouse   488 -PTFTLRKK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	82/259 (32%)
Casp8	NP_001264855.1	DED_Caspase_8_r1	23..104	CDD:260041
		DD	118..199	CDD:387368	4/13 (31%)
		CASc	247..499	CDD:237997	86/272 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842782
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.700