Protein Alignment Decay and Casp4

DIOPT Version :9

• Sequence 1: NP_477462.1
• Gene: Decay / 42008
• FlyBaseID: FBgn0028381
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_031635.2
• Gene: Casp4 / 12363
• MGIID: 107700
• Length: 373
• Species: Mus musculus
• Alignment Length: 344
• Identity: 82/344 - (23%)
• Similarity: 133/344 - (38%)
• Gaps: 75/344 - (21%)

  Fly    13 NKHKKDK----ADATKIAHTPTSELDLKRII---------------------------------- 39
            |..:.||    .||.|..|:...|:.|:...
Mouse    47 NAERSDKRWVFVDAMKKKHSKVGEMLLQTFFSVDPGSHHGEANLEMEEPEESLNTLKLCSPEEFT 111

  Fly    40 -ISRPTNEDTY---ENCARAGIALILNHKDVKGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLT 100
             :.|...::.|   |...|...|||:.:.:.|....|.|...|...|:..|:..|:||...::||
Mouse   112 RLCREKTQEIYPIKEANGRTRKALIICNTEFKHLSLRYGANFDIIGMKGLLEDLGYDVVVKEELT 176

  Fly   101 FSEINDTLKE-VAREDHSQNDCFVLAVMSHGTE----GKVYAKD----MSYPVERLWNPFLGDNC 156
            ...:...:|: .|..:|..:|...|.:|||||.    |.::::.    :.|  :.::..|...:|
Mouse   177 AEGMESEMKDFAALSEHQTSDSTFLVLMSHGTLHGICGTMHSEKTPDVLQY--DTIYQIFNNCHC 239

  Fly   157 KTLKNKPKLFFIQACRGANL-EKAVEFSSFAVMTR--ELVPEPAAAVQPITYAIPSTADILVFYS 218
            ..|::|||:..:|||||.|. |..:..||...:.|  :|.....|....:::.   ..|.:.|||
Mouse   240 PGLRDKPKVIIVQACRGGNSGEMWIRESSKPQLCRGVDLPRNMEADAVKLSHV---EKDFIAFYS 301

  Fly   219 TFDKFFSFRNVDDGSWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEAL 283
            |.....|:|:...||:||..|.....:.|.:       ..|..:...|.       ||..|....
Mouse   302 TTPHHLSYRDKTGGSYFITRLISCFRKHACS-------CHLFDIFLKVQ-------QSFEKASIH 352

  Fly   284 NQMKEMPNFMSTLTKTFQL 302
            :||..:..  :|||:.|.|
Mouse   353 SQMPTIDR--ATLTRYFYL 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	69/259 (27%)
Casp4	NP_031635.2	Required for LPS-binding. /evidence=ECO:0000269|PubMed:25119034	1..59		3/11 (27%)
		CARD_CASP1-like	5..85	CDD:260036	9/37 (24%)
		CASc	122..371	CDD:214521	72/269 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842786
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740