DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Decay and casp20

DIOPT Version :9

Sequence 1:	NP_477462.1	Gene:	Decay / 42008	FlyBaseID:	FBgn0028381	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001129724.1	Gene:	casp20 / 100192215	ZFINID:	ZDB-GENE-081022-114	Length:	347	Species:	Danio rerio

Alignment Length:	236	Identity:	85/236 - (36%)
Similarity:	121/236 - (51%)	Gaps:	20/236 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 GIALILNHKDVKGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVAREDHSQND 120
            ||.:|:|:.|....|:|.|::.|:..:....:..||:|....:.|.:|:.:.|:.:.|.  ...|
Zfish   114 GICVIINNVDFTSMKERRGSDEDQKYLAKVFRWLGFEVVAHRNKTAAEMKNILQALGRT--VDGD 176

  Fly   121 CFVLAVMSHGTEGKVYAKDMS-YPVERLWNPFLGDNCKTLKNKPKLFFIQACRGANLEKAVEFSS 184
            |||..|:|||.:..|...|.| ..|:.:.:||.|.||:.|..||||||||||||...:..|...:
Zfish   177 CFVCCVLSHGMKEGVCGTDGSLVSVDEIRDPFTGINCQKLVGKPKLFFIQACRGQRKQLRVNAQA 241

  Fly   185 FAVMTRELVPEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFIQSLCRVLDQAAAN 249
            ......|...|.......||  |||..|.|:..||.|...|:|..|:||||||||||.|
Zfish   242 DGPGDGESEMEVDGDDFDIT--IPSDTDFLIARSTTDGHVSYRKPDEGSWFIQSLCRNL------ 298

  Fly   250 EAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMP 290
            |...|.|.::|.:|.:||.:|:.        :.|:. |:||
Zfish   299 EKHCPLGADILTILLSVNNEVSI--------QGLHS-KQMP 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Decay	NP_477462.1	CASc	54..302	CDD:237997	85/236 (36%)
casp20	NP_001129724.1	CARD	10..82	CDD:260018
casp20	NP_001129724.1	CASc	106..343	CDD:237997	85/236 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587215
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840