Protein Alignment Cad89D and Pcdhb11

DIOPT Version :9

• Sequence 1: NP_650554.3
• Gene: Cad89D / 42006
• FlyBaseID: FBgn0038439
• Length: 2240
• Species: Drosophila melanogaster
• Sequence 2: NP_444366.3
• Gene: Pcdhb11 / 93882
• MGIID: 2136746
• Length: 797
• Species: Mus musculus
• Alignment Length: 1033
• Identity: 222/1033 - (21%)
• Similarity: 333/1033 - (32%)
• Gaps: 405/1033 - (39%)

  Fly   795 LLYKNGINLVNNELGTYREMPSEPTS----RNIT--MGSR---FRSRNRSRSSKSKRRLPRRLVG 850
            ||:|:|..      .|...||.|..|    .|:.  :|.|   ..:|......|..:.|   |..
Mouse    22 LLWKSGSG------ATRYSMPEEKESGYLVANVAKDLGLRVGELATRGAQIHYKGNKEL---LQM 77

  Fly   851 DANIKLRYIIANQQEVVNKISITEDGTLLTLTGLDREQQPSYELTVIVEYSTGLVSGAGIYQVNI 915
            ||                     |.|.|.....||||.........::.:...|.:....:|..:
Mouse    78 DA---------------------ETGNLFLKEKLDREALCGATEPCVLHFQVILENPVQFFQTEL 121

  Fly   916 KVDDVNDNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAEFRVQLQGDYSDEFSIE 980
            ::.|:||::|:|.....:..|.||...||...:..|   ||:|.|.||   ||
Mouse   122 QLTDINDHSPEFPDREMLLKIPENAQPGTVFPLKAA---QDSDIGSNA---VQ------------ 168

  Fly   981 YVNGTSSENSTHHKMPSTTGAFNIFNLTDQWNDEFKYQELHTTFMQTNFKLSSGPYFRISYTGKR 1045
              |.|.|.|...|.            :|...:|..||.||                     ...|
Mouse   169 --NYTVSPNIHFHV------------ITHSRSDGRKYPEL---------------------VLDR 198

  Fly  1046 GLDREKQQLYNLKIIAADTGG--LSGYAHLTVLVADVNDNAPMFERISVFKDSRLEIREYTTDME 1108
            .||||:|....|.:.|.|.|.  .||...:.:.|.|:|||||.|.:                  .
Mouse   199 ALDREEQPELTLILTALDGGAPPRSGTTIVHIEVVDINDNAPQFIQ------------------S 245

  Fly  1109 IYFVESSSGMTAPQATAAMMLAPPPYHIPGSPRFNVDRERSVGAGLGVVARAKSRRRMVRALTTK 1173
            :|.|:
Mouse   246 LYEVQ------------------------------------------------------------ 250

  Fly  1174 CPLFAIYEDTPVGTKVLQLSASDEDFGKNALLHYEL-QGEQVERTPGMPMLRVHGVKYFAIDKLS 1237
                 |.|::|:.|.|:.:||.|.|.|....:.|.| ||:.:.:.             |.||:::
Mouse   251 -----ILENSPIDTLVVTVSARDLDSGIYGNVAYSLFQGDGLSQP-------------FVIDEVT 297

  Fly  1238 GELSVNYPLS------ANIEIMLNLTVTDIDGLKDSTCLRFTVMDVNNHAPTFKKSWYSFDTPEG 1296
            ||:.::..|.      .||||    ..||...|.....:...|:|||::||.......:...||.
Mouse   298 GEIRLSKELDFEGISHYNIEI----AATDGGDLLGKCTVVIQVLDVNDNAPELMIRKLTVPVPEN 358

  Fly  1297 EYKDSVLGQLTAIDMDFGENANITYTLSDSHLPFTIKPASG---VLKIGGQLDRELKDKYSFQVI 1358
            . .::|:...:..|.|.|:|..|..:: .:::||.:||...   .|...|.||||.:.:|:..:.
Mouse   359 S-AETVVAVFSVSDSDSGDNGRIVCSI-QNNIPFLLKPTFENYYTLVTEGPLDRESRAEYNITIT 421

  Fly  1359 ATD-NAPVMQRMSSSVDVEVNVLDINDNRPEFIGYDDQTKAVKFIPSVADRTLMLPVYKAYLDRS 1422
            ..| ..|   |:::...:.|.|.|||||.|.|    .||....|:
Mouse   422 VWDLGTP---RLTTQHTITVQVSDINDNAPAF----TQTSYTLFV-------------------- 459

  Fly  1423 TQPGTFVRQLTAIDKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRDGTISTISRINGYNDYEHLNV 1487
                                           ||..:|..||    ||||.....:|.|  .|:..
Mouse   460 -------------------------------QENNSPALQI----GTISATDSDSGSN--AHITY 487

  Fly  1488 SVIASDVGSPALSATAIVIVNLQGQAVTDPPKSTPKPEPPANVTVFQHAYYEVKLTENNEAPIEV 1552
            |::...  .|.|:..:::
Mouse   488 SLLLPQ--DPQLALASLI----------------------------------------------- 503

  Fly  1553 MRLNLSAGLNPENYRWSLWLEEGLDETDAHPPFEYDAKNMLLYALKPFDREHISRYQLRIRADRL 1617
                   .:||:|.:                          |:.|:..|.|.:..::.|:.|
Mouse   504 -------SINPDNGQ--------------------------LFVLRALDYESLQAFEFRVGA--- 532

  Fly  1618 SREARNYARVSYPVVDERIEGLSLNECRILVHIADENDNAP----KFRGNGQPIVAVLPQSASFG 1678
                          .|:....|| ::..:.|.:.|:|||||    ..:....|...:||:.|..|
Mouse   533 --------------TDQGSPALS-SQTLVRVVVLDDNDNAPFVLYPMQNASAPCTELLPREAESG 582

  Fly  1679 YPVTRVEANDLDEGLNAEIRYRLL--NEPARLFGIDELSGNI---RLLGELSRTEHIYGFDVKAT 1738
            |.||:|.|.|.|.|.||.:.::||  .||. ||.:...:|.:   |||.|....:|.....||
Mouse   583 YLVTKVVAVDRDSGQNAWLSFQLLKATEPG-LFSVWAHNGEVRTTRLLSERDVPKHRLLLLVK-- 644

  Fly  1739 DRMGADDGR---SGIVNVFVYIINEAKQVRLVVAGMPVEVERRIEGLMEALSDAIGKD 1793
                 |:|.   |..|.:.|.::|...|..|              .|.|...|.|.:|
Mouse   645 -----DNGEPQLSASVTLQVLLVNSFSQPYL--------------SLPEVAQDPIQED 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad89D	NP_650554.3	Cadherin_repeat	183..290	CDD:206637
		Cadherin_repeat	325..407	CDD:206637
		Cadherin_repeat	416..524	CDD:206637
		Cadherin_repeat	534..626	CDD:206637
		Cadherin_repeat	641..>714	CDD:206637
		CA	851..925	CDD:214520	14/73 (19%)
		CA	1026..1085	CDD:214520	17/60 (28%)
		Cadherin_repeat	1177..1280	CDD:206637	31/109 (28%)
		Cadherin_repeat	1289..1385	CDD:206637	27/99 (27%)
		Cadherin_repeat	1414..1510	CDD:206637	15/95 (16%)
		CA	1576..1658	CDD:214520	14/81 (17%)
		Cadherin_repeat	1666..1760	CDD:206637	34/101 (34%)
Pcdhb11	NP_444366.3	Cadherin_2	32..112	CDD:285466	21/103 (20%)
		Cadherin_repeat	140..238	CDD:206637	40/150 (27%)
		Cadherin_repeat	247..342	CDD:206637	33/176 (19%)
		Cadherin_repeat	352..446	CDD:206637	27/98 (28%)
		Cadherin_repeat	454..556	CDD:206637	31/258 (12%)
		Cadherin_repeat	575..662	CDD:206637	33/94 (35%)
		Cadherin_C_2	687..769	CDD:293101

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000