Protein Alignment Cad89D and Pcdhga2

DIOPT Version :9

• Sequence 1: NP_650554.3
• Gene: Cad89D / 42006
• FlyBaseID: FBgn0038439
• Length: 2240
• Species: Drosophila melanogaster
• Sequence 2: NP_001032216.1
• Gene: Pcdhga2 / 498846
• RGDID: 1587259
• Length: 931
• Species: Rattus norvegicus
• Alignment Length: 987
• Identity: 218/987 - (22%)
• Similarity: 331/987 - (33%)
• Gaps: 394/987 - (39%)

  Fly   763 QKVP----------LRPVIEEINMNVIHFHVEENV-VGGIIGQLLYKNGINLVNNELGTYREMPS 816
            ||:|          |...:.|.....|.:.|.|.: .|..:|.:....|:.            |.
  Rat     5 QKLPQSRMLVLLCALWAALWEARAGQIRYSVPEEIDKGSFVGSIAKDLGLE------------PR 57

  Fly   817 EPTSRNITMGSRFRSRNRSRSSKSKRRLPRRLVGDANIKLRYIIANQQEVVNKISITEDGTLLTL 881
            ....|.:.:.||.:|:..:.:.:|                                   |:|:|.
  Rat    58 ALEERGVRIVSRGKSQLFALNPRS-----------------------------------GSLVTA 87

  Fly   882 TGLDREQQPSYELTVIVEYSTGLVSGAGIYQVNIKVDDVNDNAPKFNALTYVGLINENCVVGTEL 946
            ..:|||:..:.....:|.::..:.....||.|.::|.|||||||:|........|:|....|..:
  Rat    88 GRIDREELCAQSTPCLVNFNLLMEDKLTIYSVEVEVIDVNDNAPRFGVEEPELKISETTTPGFRI 152

  Fly   947 SMNHAILIQDADEGPNAEFRVQLQGDYSDEFSIEYVNGTSSENSTHHKMPSTTGAFNIFNLTDQW 1011
            .:..|   .|||.|.|...:.:|..  :|.||::.                .|||
  Rat   153 PLKSA---HDADVGENTLQKYKLNS--NDHFSLDV----------------RTGA---------- 186

  Fly  1012 NDEFKYQELHTTFMQTNFKLSSGPYFRISYTGKRGLDREKQQLYNLKIIAADTGG--LSGYAHLT 1074
             |..||.||                     ..:|.||||::.:::|.::|:|.|.  .|....:.
  Rat   187 -DGNKYPEL---------------------VLERALDREEEAVHHLVLVASDRGKPVRSSTCRIR 229

  Fly  1075 VLVADVNDNAPMFERISVFKDSRLEIREYTTDMEIYFVESSSGMTAPQATAAMMLAPPPYHIPGS 1139
            |.|.|||||||:|.:                                          |.|.:
  Rat   230 VKVLDVNDNAPVFTQ------------------------------------------PEYRV--- 249

  Fly  1140 PRFNVDRERSVGAGLGVVARAKSRRRMVRALTTKCPLFAIYEDTPVGTKVLQLSASDEDFGKNAL 1204
                                                  ::.|:.||||::|.::|:|.|.|.||.
  Rat   250 --------------------------------------SVPENMPVGTRILTVTATDTDEGYNAQ 276

  Fly  1205 LHYELQGEQVERTPGMPMLRVHGVKYFAIDKLSGEL----SVNYPLSANIEIMLNLTVTDIDGLK 1265
            :.|.|     ||.||      .....|.:...||::    |::|..:...||  ::...|..||.
  Rat   277 VTYFL-----ERVPG------ESTDAFELKSTSGDITITKSLDYEKAKFHEI--DIEAQDGPGLL 328

  Fly  1266 DSTCLRFTVMDVNNHAPTFKKSWYSFDTPEGEYKDSVLGQLTAI----DMDFGENANITYTLSDS 1326
            ..|.:..||:|||::||.|..:..:...||    |:.||.:.|:    |.|.|:||.:|.:|.:.
  Rat   329 TRTKVIVTVLDVNDNAPEFYMTSATASVPE----DAPLGTVIALFNVHDRDSGQNAVVTCSLPEM 389

  Fly  1327 HLPFTIKPASG---VLKIGGQLDRELKDKYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPE 1388
             |||.::.:..   .|.....||||....|:..:.|.|..  ...:|:...:.:.|.|||||.|.
  Rat   390 -LPFKLERSVDNYYRLVTTRALDREQFSFYNITLRAKDQG--SPSLSTDAHLLLQVADINDNPPS 451

  Fly  1389 FIGYDDQTKAVKFIPSVADRTLMLPVYKAYLDRSTQPGTFVRQLTAIDKDNVGNGNGLVLYSIRH 1453
            |                     ....|.||:..:...||.:..:.|.|.|:  |.|..|.||:..
  Rat   452 F---------------------SRGAYSAYIPENNPRGTSIFSVLAYDPDS--NDNAHVTYSLAE 493

  Fly  1454 QEMQ-APL---FQIDSRDGTISTISRINGYNDYEHLNVSVIASDVGSPALSATAIVIVNLQGQAV 1514
            ...| |||   ..|:|..|.:..: |...|..::.|.:.|||.|.|.|.||
  Rat   494 DTFQGAPLSSYISINSDTGVLYAL-RSFDYEQFQDLQLWVIAVDSGKPPLS-------------- 543

  Fly  1515 TDPPKSTPKPEPPANVTVFQHAYYEVKLTENNEAPIEVMRLNLSAGLNPENYRWSLWLEEGLDET 1579
                         :||::                                    ||:|   :|:.
  Rat   544 -------------SNVSL------------------------------------SLFL---VDQN 556

  Fly  1580 DAHPPFEYDAKNMLLYALKPFDREHISRYQLRIRADRLSREARNYARVSYPVVDERIEGLSLNEC 1644
            |..|.        :||...|.|
  Rat   557 DNMPE--------ILYPALPTD------------------------------------------- 570

  Fly  1645 RILVHIADENDNAPKFRGNGQPIVAVLPQSASFGYPVTRVEANDLDEGLNAEIRYRLL--NEPAR 1707
                               |...|.:.|:||..||.||:|.|.|.|.|.||.:.||||  :||.
  Rat   571 -------------------GSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPG- 615

  Fly  1708 LFGIDELSGNIR 1719
            ||.:...:|.:|
  Rat   616 LFSVGLHTGEVR 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad89D	NP_650554.3	Cadherin_repeat	183..290	CDD:206637
		Cadherin_repeat	325..407	CDD:206637
		Cadherin_repeat	416..524	CDD:206637
		Cadherin_repeat	534..626	CDD:206637
		Cadherin_repeat	641..>714	CDD:206637
		CA	851..925	CDD:214520	16/73 (22%)
		CA	1026..1085	CDD:214520	17/60 (28%)
		Cadherin_repeat	1177..1280	CDD:206637	34/106 (32%)
		Cadherin_repeat	1289..1385	CDD:206637	29/102 (28%)
		Cadherin_repeat	1414..1510	CDD:206637	31/99 (31%)
		CA	1576..1658	CDD:214520	7/81 (9%)
		Cadherin_repeat	1666..1760	CDD:206637	25/56 (45%)
Pcdhga2	NP_001032216.1	Cadherin_2	30..112	CDD:285466	19/128 (15%)
		Cadherin_repeat	139..238	CDD:206637	36/151 (24%)
		Cadherin_repeat	246..343	CDD:206637	35/150 (23%)
		Cadherin_repeat	353..448	CDD:206637	29/101 (29%)
		Cadherin_repeat	457..558	CDD:206637	37/169 (22%)
		Cadherin_repeat	579..666	CDD:206637	24/50 (48%)
		Cadherin_C_2	688..772	CDD:293101
		Cadherin_tail	808..>904	CDD:292596

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910