Protein Alignment Cad89D and cdh-7

DIOPT Version :9

• Sequence 1: NP_650554.3
• Gene: Cad89D / 42006
• FlyBaseID: FBgn0038439
• Length: 2240
• Species: Drosophila melanogaster
• Sequence 2: NP_497075.2
• Gene: cdh-7 / 175143
• WormBaseID: WBGene00000399
• Length: 1364
• Species: Caenorhabditis elegans
• Alignment Length: 1544
• Identity: 301/1544 - (19%)
• Similarity: 529/1544 - (34%)
• Gaps: 497/1544 - (32%)

  Fly   160 GSYLSITVYIEDVNDNA--------PEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSE 216
            |..|||......:..||        |||:...  .|:||..::|   .||
 Worm    18 GDLLSIPSTTFKIPRNAQEGDLIIGPEFIRAS--EDIDEALNLE---LEG--------------- 62

  Fly   217 VHFSMSTVPEQLSADGSPYFALKSPHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPANQANTTI 281
                  |.|..::.:||...| ..|.:.:|:.|..  ||:|..:.||.......|....:   ||
 Worm    63 ------TNPSPIAINGSIIDA-GQPVKFILVNKNA--FDSGKSKVKLQAIGVISGKVQEE---TI 115

  Fly   282 TINVRDVDDLP--PKFTEGVYRTRINEFYPMTGVPIRI--PLYFAPPIMAFDQDSLNASLVYDII 342
            ...|....|||  |:.:..|.:   ::|.......:|:  |:   ||         |:.|  ||:
 Worm   116 NFEVEASSDLPSIPEISNFVVK---SDFQEKETAIVRVSSPI---PP---------NSEL--DIL 163

  Fly   343 SGNERQLFRVNPHNGVMYLQK-EIDLEEESLPGNT--------------FVLQLEARQKDNPLKK 392
            ..               |.|: ....|::.:..||              ||:.|..|..:|.::.
 Worm   164 GS---------------YAQRVTATFEDDKIILNTVPCHADTPCEVTFPFVVILVLRNGENHVEA 213

  Fly   393 ALARIEVEVLDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLVETKDAA 457
            .|...|.:...|     :.....|..:|.|:......:::::.    :|.:||.||:|   :||:
 Worm   214 LLTFQEEKKSSL-----KMAQKLYQTTIEEHTGEQDHLVKIST----KGGSSEVLYSL---RDAS 266

  Fly   458 GAFRIDSRTGWITVRDDRLL----------------DREQRRSIQLNVE---ALERNPSYLDDKH 503
            |.|.|..:.|.:::.....|                |.::.....:||:   .:|:|..:
 Worm   267 GLFSIHPKEGILSILHPEFLSISSFGDTVNLTVVATDGDKTADAMINVKIVPEVEKNVVF----- 326

  Fly   504 LKKPGPSKVQVEITLLDTNDNTPKFEHGNLYEFKVPINAPTGYVI--GQVVAHDPDEGPNGHLLY 566
                |..|...:||..:.|...     ||:   |....:|..|.|  |::..:..:  |||.|:|
 Worm   327 ----GFEKESYDITAENINSIL-----GNI---KAKSASPVVYRITEGRIDLYKVE--PNGDLVY 377

  Fly   567 ELQRPKGSGYIPFRLDNKNGTIYVGGPLRRGRIAVFVEATDQPTNPSERRFSLAVITIEVYATID 631
            ..:..||.     |.|:....:..|| |:.....|.:......:||......|..|.:
 Worm   378 TGKMVKGD-----REDDVTVVVQQGG-LKMASTKVHINLKGIGSNPVSTSDELEKIEL------- 429

  Fly   632 DQAIDFVGAPYEFWVGANTPLGTSVGQVRTTLIYEGGDEIMYDLLHTYSEGVPFAIEERSGIITV 696
                          :.:..|.|..|    |.:.::..|:   |...||...:...::|...:|.:
 Worm   430 --------------ISSEDPNGVVV----TLIQFQDEDK---DAKLTYELTMENGVDENGNMIPL 473

  Fly   697 IRELSEFKRKVYQFEAVANYLFANSSQSLVMSRS--SSPLTTI---------ASPAELSDEGVLI 750
            ..:|.|.|.:    |.||:         ||:|.:  :|.:|||         ..|.|.|   |.:
 Worm   474 QEQLFEIKSE----EKVAH---------LVVSGNLKTSKITTILLKITARDSTHPKEPS---VTV 522

  Fly   751 TNLTIHIVNKPEQKVPLRPVIEEINMNVIHFHVEENV-VGGIIGQLLYKNGINLVNNELGTYREM 814
            |.|.:....|.|:        |.:.:|:|....|..| |...:|..:||
 Worm   523 TRLIVIQREKSEE--------EPMGLNLIPLPTEILVPVDSAVGSFIYK---------------- 563

  Fly   815 PSEPTSRNITMGSRFRSRNRSRSSKSKRRLPRRLVGDANIKLRYIIANQQEVVNKISITEDGTLL 879
                    :|:                  ||.:      ..|:|.|    |..:...|.:||:::
 Worm   564 --------VTV------------------LPMK------ENLQYSI----EPEHLFQILDDGSIV 592

  Fly   880 TLTGLDREQQPSYELTVIVEYSTGLVSGAGIYQVNIKVD----------DVN--DNAPKFNALTY 932
            |...|..|.:   :|.:.||.|.|....:....:.:|..          ||.  ...||.:.:|.
 Worm   593 TQKELTVEAE---QLKIHVEVSDGSEKKSTETTLTLKKTLHPHFTESRYDVTLPRQTPKDSVITV 654

  Fly   933 VGLINENCVVGTELSMNHAILIQDADEGPNAEFRVQLQGDYSDEFSIEYVNGTSSENSTHHKMPS 997
            |..:..|                    |......|..:|.:|..|.|:
 Worm   655 VSAVGGN--------------------GEPVNQFVLKKGGHSKHFKID----------------- 682

  Fly   998 TTGAFNIFNLTDQWNDEFKYQELHTTFMQTNFKLSSGPYFRISYTGKRGLDREKQQLYNLKIIAA 1062
            ..||..:.:..::::|                                 ||.|    .:|.:..|
 Worm   683 EKGALRLADEQERFDD---------------------------------LDDE----MDLLVALA 710

  Fly  1063 DTGGLSGYAHLTV--------------LVADVNDNAPMFERISVFKDSRLEI--REYTTD----M 1107
            :...:|...|:::              :.|.|.||.|:...:...:.:..|:  .|.|:|    .
 Worm   711 ENPTISVPVHISLKKNRNPRIDLVENQIFATVYDNLPINSYVGKVEVASKELVKFEMTSDEKGMS 775

  Fly  1108 EIYFVESSSGMTAPQATAAMMLAPPPYHIPGSPRF-----NVDRE--RSVGAGLGVVARAKSRRR 1165
            .::.:|....:.:....|..         .|..:|     |:|:.  ||..|.: |:...||...
 Worm   776 SLFGIEEDGTIRSKDWLAGS---------EGMHKFSVLASNIDQAGVRSANATV-VIDVIKSNEC 830

  Fly  1166 MVRALTTKCPLFAIYEDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKY 1230
            ..:....:..:|.:.|:||:.|.:.::|| |...||.| |.|.:.|...|              .
 Worm   831 SPKFKRDENLIFYVRENTPIDTVIGKVSA-DVLPGKCA-LEYSIIGPNSE--------------I 879

  Fly  1231 FAIDKLSGELSVNYPLSANIEIMLNLTVTDIDGLKDS--TCLRFTVMDVNNHAPTFKKSWYSFDT 1293
            .:|:..:|||..:.......:....||:..:.|..:|  :.....::||::|...|:....:.:.
 Worm   880 LSINSANGELKTSKEFDFEKQKSYLLTLKLVAGKYNSVESGAELKILDVDDHEVKFELQEQTVEI 944

  Fly  1294 PEGEYKDSVLGQLTAIDMDFGENANITYTLSDSHLP-FTIKPASGVLKIGGQLDRELKDKYSFQV 1357
            ||....::|:..:.|.:.|  |:..:.|.|.....| |::...:|.:.:...||||..|.:..::
 Worm   945 PEDAPLNTVVATVKATEGD--ESQEVFYHLKAGSPPQFSLNSKTGEVMVEQALDREALDNFEIEI 1007

  Fly  1358 IATDNAPVMQRMSSSVDVEVNVLDINDNRPEFIGYDDQTKAVKFIPSVADRTLMLPVYKAYLDRS 1422
            .|:::..::.  ::::.:.|.|.|:|||.|.|                 ||    |.|...:.:.
 Worm  1008 GASNSVDLIG--TAAMKLLVKVKDVNDNGPTF-----------------DR----PQYFTVVSKD 1049

  Fly  1423 TQPGTFVRQLTAIDKD------------------------NV-------GNGNGLVLYSIRHQEM 1456
            |..|..:.:|.|.|.|                        ||       |..|..:..|....:.
 Worm  1050 TVVGAELLELNAYDPDLSDQEKKLEYTVTASSFEYRGMSRNVEDVLDIRGGENPKIYLSKPLTDY 1114

  Fly  1457 QAPLFQI-----DSRDGTISTISRINGYNDYEHLNVSVIASDVG-SPALSATAIV---IVNLQGQ 1512
            ...:|.:     |:.||||..    :....|.|.:..:::.::. ||:..:..::   ..||...
 Worm  1115 VGGVFNVQLQVRDTVDGTIGK----SALRVYVHDSSDLLSLELPYSPSTVSQGVIQEFTENLSNS 1175

  Fly  1513 -AVTDPPKSTPKPEPPANVTVFQHAYYEVK--LTENNEAPIEVMRLNLS 1558
             .:|..|||               .||:..  :...|...::|:..|.|
 Worm  1176 TGLTAIPKS---------------VYYKAPHGIMSTNSIDLQVIFFNKS 1209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad89D	NP_650554.3	Cadherin_repeat	183..290	CDD:206637	23/106 (22%)
		Cadherin_repeat	325..407	CDD:206637	17/96 (18%)
		Cadherin_repeat	416..524	CDD:206637	26/126 (21%)
		Cadherin_repeat	534..626	CDD:206637	22/93 (24%)
		Cadherin_repeat	641..>714	CDD:206637	14/72 (19%)
		CA	851..925	CDD:214520	18/85 (21%)
		CA	1026..1085	CDD:214520	11/72 (15%)
		Cadherin_repeat	1177..1280	CDD:206637	25/104 (24%)
		Cadherin_repeat	1289..1385	CDD:206637	21/96 (22%)
		Cadherin_repeat	1414..1510	CDD:206637	23/135 (17%)
		CA	1576..1658	CDD:214520
		Cadherin_repeat	1666..1760	CDD:206637
cdh-7	NP_497075.2	Cadherin_repeat	232..319	CDD:206637	19/93 (20%)
		Cadherin_repeat	548..>613	CDD:206637	23/119 (19%)
		Cadherin_repeat	842..931	CDD:206637	25/104 (24%)
		Cadherin_repeat	939..1033	CDD:206637	21/97 (22%)
		Cadherin_repeat	1041..1147	CDD:206637	20/109 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24026
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100