Protein Alignment Cad89D and AgaP_AGAP003607

DIOPT Version :9

• Sequence 1: NP_650554.3
• Gene: Cad89D / 42006
• FlyBaseID: FBgn0038439
• Length: 2240
• Species: Drosophila melanogaster
• Sequence 2: XP_313367.4
• Gene: AgaP_AGAP003607 / 1274271
• VectorBaseID: AGAP003607
• Length: 746
• Species: Anopheles gambiae
• Alignment Length: 647
• Identity: 152/647 - (23%)
• Similarity: 251/647 - (38%)
• Gaps: 172/647 - (26%)

  Fly    63 LDGVAAESEGVRFIRLREDAQVGKEI--LRLQAYPRSTAALKGADASGDHKYFNLTEHNATTLVV 125
            |||   ....|.|. ..||..||..:  ||:...|            |......|.|.::...:.
Mosquito    32 LDG---GGSAVNFF-ANEDITVGAVVGSLRVLGDP------------GKDIVLTLREKDSPVYIA 80

  Fly   126 SLARSL--ERLVDRD--VPRNLLKFRILCAGK---QEKLEEGSYLSITVYIEDVNDNAPEFLNVP 183
            ...:.|  .:.:|::  :..:.:...::|..|   :...|.|..:.:.:.:.|||||||.::..|
Mosquito    81 PGTKDLIVAKPLDKEGLIGPSAVFVNVICERKFSDEAVRERGIIIPVNIRVTDVNDNAPMWIGAP 145

  Fly   184 YVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMSTVPEQLSADGSPYFALKSPHRPLLIL 248
            |.:::.|.|.|.:.|.:|::|.|.|:|. |.|.|.:      :.|....|.:.|..:|....|:|
Mosquito   146 YKLNLSEVTVIGTRILQGIRAHDLDQPG-PYSTVEY------QTLPGPYSDFVAFVTPLEGTLVL 203

  Fly   249 KRELDFDNGIRQFKLPIFAWDRGTPANQANTTITINVRDVDDLPPKFTEGVYRTRINEFYPMTGV 313
            |:.:|::. ::.|.:.|.|.|:|.|...::|.:||.|.|.||..|||...||..::
Mosquito   204 KKYIDYET-VQNFTVKIRAQDQGKPPKYSDTYVTIRVLDSDDQNPKFDRDVYYGQL--------- 258

  Fly   314 PIRIPLYFAPP---------IMAFDQD-SLNASLVYDIIS--GNERQL-FRVNPHNGVMYLQKEI 365
                   .|.|         |.|.||| .:.|.:.|.|:|  |:|.:| |.::|..|.:
Mosquito   259 -------LAGPGDVSITPETIRAEDQDRGIRADIRYSIVSSNGSEDELNFEIHPTTGTI------ 310

  Fly   366 DLEEESLP------GNTFVLQLEARQKDNPLKKALARI--------EVEVLDLNDNVP----EFE 412
             .:..:||      ..|.|  ::|.|.|||.:.||..:        |..:..::...|    ||.
Mosquito   311 -RQRRALPPAQAHHSRTIV--VKATQVDNPDRYALTTVILAPPKGSETSLSAMSVQPPVGGAEFV 372

  Fly   413 ADYYNISIVENLPTGFSVLQVNAVDRDQGENSE-FLYNLVETKDAAGAFRID------------- 463
            ...:.:::.|:...|..|.|:  |....|...| ..|.:|.:..|...||:.
Mosquito   373 RGTFYVTVREDAAPGTKVSQL--VPGGGGRADEPVRYRIVGSPLAQEQFRVGPGGELMLARSLNY 435

  Fly   464 SRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEITLLDTNDNTPKF 528
            .||...|.            :|:.::...|||.|              ..|.:.:|..|...|:|
Mosquito   436 RRTSQYTF------------AIESSLPGGERNTS--------------TTVVVDVLPANMWEPRF 474

  Fly   529 EHGNLYEFKV--PINA-PTGYVIGQVVAHDPDEGPNGHLLYELQRPKGSGYIPFRLDNKNGTIYV 590
            .. ..|.|.:  |::| ....::|::.|.|.|.  ...|.:.|   ||:....||:|
Mosquito   475 RK-PFYSFAIENPLHAQQLPMLVGRIEAADGDR--TDELSFVL---KGNYSNLFRVD-------- 525

  Fly   591 GGPLRRGRIAVFVEATDQPTNPSERRFSLAVITIEVYATIDDQAIDFVGAPYEFWVGANTPL 652
              |.  |.:.:....||.|            :.:.:.||:.|.     |.|.:   .|..|:
Mosquito   526 --PY--GNLWLVSNRTDLP------------LAMRLLATVTDS-----GTPQK---SATVPV 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad89D	NP_650554.3	Cadherin_repeat	183..290	CDD:206637	33/106 (31%)
		Cadherin_repeat	325..407	CDD:206637	27/99 (27%)
		Cadherin_repeat	416..524	CDD:206637	23/121 (19%)
		Cadherin_repeat	534..626	CDD:206637	20/94 (21%)
		Cadherin_repeat	641..>714	CDD:206637	3/12 (25%)
		CA	851..925	CDD:214520
		CA	1026..1085	CDD:214520
		Cadherin_repeat	1177..1280	CDD:206637
		Cadherin_repeat	1289..1385	CDD:206637
		Cadherin_repeat	1414..1510	CDD:206637
		CA	1576..1658	CDD:214520
		Cadherin_repeat	1666..1760	CDD:206637
AgaP_AGAP003607	XP_313367.4	E_set	<74..139	CDD:298831	11/64 (17%)
		Cadherin_repeat	145..244	CDD:206637	33/106 (31%)
		Cadherin_repeat	271..347	CDD:206637	26/84 (31%)
		Cadherin_repeat	375..468	CDD:206637	22/120 (18%)
		Cadherin_repeat	479..570	CDD:206637	27/122 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910