DRSC/TRiP Functional Genomics Resources

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Protein Alignment Der-2 and Derl1

DIOPT Version :9

Sequence 1:NP_650553.1 Gene:Der-2 / 42005 FlyBaseID:FBgn0038438 Length:261 Species:Drosophila melanogaster
Sequence 2:NP_077169.1 Gene:Derl1 / 67819 MGIID:1915069 Length:251 Species:Mus musculus


Alignment Length:247 Identity:77/247 - (31%)
Similarity:121/247 - (48%) Gaps:19/247 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MNALRQFYLEIPVVTRAYTTVCVLTTLAVHLDLVSPLQLYFNPTLIVRKFQIWRLATTFLYF--- 62
            |:.:..::..||.:||.:....|...|...|.::||...:..|...:.:|||||..|...||   
Mouse     1 MSDIGDWFRSIPAITRYWFAATVAVPLIGKLGIISPAYFFLWPEAFLYRFQIWRPFTATFYFPVG 65

  Fly    63 -GTIGISFFFNMVFTYRYCRMLEDGSFRGRSSDFVMMFIFGGVLMTFFGIFVNLLFLGQAFTLML 126
             || |..:..|:.|.|:|...||.|:|.||.:|::.|.:|..:.:...|:.:::..|.....:.:
Mouse    66 PGT-GFLYLVNLYFLYQYSTRLEAGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIMSV 129

  Fly   127 VYVWSRRNPLVPMNFFGVLNFQAPYLPWVLLCCSMILGNTVWVDVIGMGVGHIYYVLEDVYPTLS 191
            :|||::.|..:.::|:....|:|.|||||:|..:.|:|.:|..::||..|||:|:.|...||...
Mouse   130 LYVWAQLNRDLIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDL 194

  Fly   192 NGYRLIKTPYFLKRLFNEHIERNFQAAAEDRPGGFPWGGEGQPLLPEEIAAD 243
            .|...:.||.||.|..            ..|.||.  .|.|.|......|||
Mouse   195 GGRNFLSTPQFLYRWL------------PSRRGGV--SGFGVPPASMRRAAD 232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Der-2NP_650553.1 DER1 11..201 CDD:282380 63/193 (33%)
Derl1NP_077169.1 DER1 11..204 CDD:398288 63/193 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 229..251 3/4 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5291
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54051
OrthoDB 1 1.010 - - D1609512at2759
OrthoFinder 1 1.000 - - FOG0000789
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2482
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
65.860

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