DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Der-2 and derl3

DIOPT Version :9

Sequence 1:	NP_650553.1	Gene:	Der-2 / 42005	FlyBaseID:	FBgn0038438	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_957197.2	Gene:	derl3 / 393877	ZFINID:	ZDB-GENE-040426-1324	Length:	247	Species:	Danio rerio

Alignment Length:	252	Identity:	149/252 - (59%)
Similarity:	190/252 - (75%)	Gaps:	11/252 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NALRQFYLEIPVVTRAYTTVCVLTTLAVHLDLVSPLQLYFNPTLIVRKFQIWRLATTFLYFGTIG 66
            |::.|.|::||.|||||||.|||||.||.|:|::|.||||||.||::|:|||||.|.||:||.:|
Zfish     3 NSVTQEYMQIPAVTRAYTTACVLTTAAVQLELITPFQLYFNPDLILKKYQIWRLITNFLFFGPLG 67

  Fly    67 ISFFFNMVFTYRYCRMLEDGSFRGRSSDFVMMFIFGGVLMTFFGIFVNLLFLGQAFTLMLVYVWS 131
            .||.|||:|.||||||||:||||||::|||.||:|||||||.||:|.||.|||||||:|||||||
Zfish    68 FSFLFNMIFLYRYCRMLEEGSFRGRTADFVYMFLFGGVLMTLFGLFSNLFFLGQAFTIMLVYVWS 132

  Fly   132 RRNPLVPMNFFGVLNFQAPYLPWVLLCCSMILGNTVWVDVIGMGVGHIYYVLEDVYPTLSNGYRL 196
            ||||.|.|||||:||||||:|||||:..|::|||::.:|::|:|||||||.||||:|....|.:|
Zfish   133 RRNPFVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIVIDLLGIGVGHIYYFLEDVFPNQPGGRKL 197

  Fly   197 IKTPYFLKRLFNEHIE-RNFQAAAEDRPGGFPWGGEGQPLLPEEIAADGQDEEPANR 252
            :.||...:.||:...| .|:....||: .|..|.|:|         .:.|:|:...|
Zfish   198 LATPGIFRFLFDPPQEDPNYAPLPEDQ-SGMSWNGQG---------VEDQNEDDLQR 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Der-2	NP_650553.1	DER1	11..201	CDD:282380	132/189 (70%)
derl3	NP_957197.2	DER1	12..201	CDD:282380	131/188 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589415
Domainoid	1	1.000	296	1.000	Domainoid score	I1449
eggNOG	1	0.900	-	-		E1_COG5291
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I2438
OMA	1	1.010	-	-		QHG54051
OrthoDB	1	1.010	-	-		D1609512at2759
OrthoFinder	1	1.000	-	-		FOG0000789
OrthoInspector	1	1.000	-	-		otm25604
orthoMCL	1	0.900	-	-		OOG6_101672
Panther	1	1.100	-	-	O	PTHR11009
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2482
SonicParanoid	1	1.000	-	-		X1827
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800