Protein Alignment Dhfr and DFR1

DIOPT Version :10

• Sequence 1: NP_732147.1
• Gene: Dhfr / 42003
• FlyBaseID: FBgn0004087
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_014879.1
• Gene: DFR1 / 854411
• SGDID: S000005762
• Length: 211
• Species: Saccharomyces cerevisiae
• Alignment Length: 204
• Identity: 67/204 - (32%)
• Similarity: 103/204 - (50%)
• Gaps: 33/204 - (16%)

  Fly     6 LIVAVCENFGIGIRGDLPWRIKSELKYFSRTTKRTSDPTKQNAVVMGRKTYFGVPESKRPLPDRL 70
            ::..:....|||.||.||||:.||:|||.:.|..|.||.|:||::|||||:..:|...||||:|:
Yeast    11 IVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRM 75

  Fly    71 NIVLSTTLQES---DLPKGVLLCPNLETAMKILEE--QNEVENIWIVGGSGVYEEAMASPRCHRL 130
            |:::|.:.::.   |..:.::...:|..|:..||.  :..:|.|:::||..||.: :.|...|.|
Yeast    76 NVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESNFKEHLERIYVIGGGEVYSQ-IFSITDHWL 139

  Fly   131 YITKIMQKFD------CDTFFPA----------IPDSFREVAP--------DSDMPLGVQEENGI 171
             |||| ...|      .|||..|          .|...:|..|        |.|....: ||.|.
Yeast   140 -ITKI-NPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSL-EEKGY 201

  Fly   172 KFEYKILEK 180
            .||:.:..:
Yeast   202 CFEFTLYNR 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhfr	NP_732147.1	DHFR	4..179	CDD:238127	67/201 (33%)
DFR1	NP_014879.1	DHFR	8..208	CDD:238127	67/200 (34%)