Protein Alignment Dhfr and Dhfr

DIOPT Version :10

• Sequence 1: NP_732147.1
• Gene: Dhfr / 42003
• FlyBaseID: FBgn0004087
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_569084.1
• Gene: Dhfr / 24312
• RGDID: 2500
• Length: 187
• Species: Rattus norvegicus
• Alignment Length: 187
• Identity: 89/187 - (47%)
• Similarity: 127/187 - (67%)
• Gaps: 9/187 - (4%)

  Fly     1 MLR-FNLIVAVCENFGIGIRGDLPW-RIKSELKYFSRTTKRTSDPTKQNAVVMGRKTYFGVPESK 63
            |:| .|.||||.:|.|||..||||| .:::|.|||.|.|..:|...|||.|:|||||:|.:||..
  Rat     1 MVRPLNCIVAVSQNMGIGKNGDLPWPLLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKN 65

  Fly    64 RPLPDRLNIVLSTTLQESDLPKGV-LLCPNLETAMKILEE---QNEVENIWIVGGSGVYEEAMAS 124
            |||.||:|||||..|:|.  |:|. .|..:|:.|:|::|:   .::|:.:|:||||.||:|||..
  Rat    66 RPLKDRINIVLSRELKEP--PQGAHFLAKSLDDALKLIEQPELASKVDMVWVVGGSSVYQEAMNQ 128

  Fly   125 PRCHRLYITKIMQKFDCDTFFPAIPDSFREVAPDSDMPLG-VQEENGIKFEYKILEK 180
            |...||::|:|||:|:.|||||.|.....::.|:....|. :|||.|||:::::.||
  Rat   129 PGHLRLFVTRIMQEFESDTFFPEIDLEKYKLLPEYPGVLSEIQEEKGIKYKFEVYEK 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhfr	NP_732147.1	DHFR	4..179	CDD:238127	85/180 (47%)
Dhfr	NP_569084.1	DHFR	5..184	CDD:238127	87/182 (48%)