Protein Alignment Dhfr and Dhfr

DIOPT Version :10

• Sequence 1: NP_732147.1
• Gene: Dhfr / 42003
• FlyBaseID: FBgn0004087
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_034179.1
• Gene: Dhfr / 13361
• MGIID: 94890
• Length: 187
• Species: Mus musculus
• Alignment Length: 187
• Identity: 90/187 - (48%)
• Similarity: 127/187 - (67%)
• Gaps: 9/187 - (4%)

  Fly     1 MLR-FNLIVAVCENFGIGIRGDLPW-RIKSELKYFSRTTKRTSDPTKQNAVVMGRKTYFGVPESK 63
            |:| .|.||||.:|.|||..||||| .:::|.|||.|.|..:|...|||.|:|||||:|.:||..
Mouse     1 MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKN 65

  Fly    64 RPLPDRLNIVLSTTLQESDLPKGV-LLCPNLETAMKILEE---QNEVENIWIVGGSGVYEEAMAS 124
            |||.||:|||||..|:|.  |:|. .|..:|:.|::::|:   .::|:.:||||||.||:|||..
Mouse    66 RPLKDRINIVLSRELKEP--PRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQ 128

  Fly   125 PRCHRLYITKIMQKFDCDTFFPAIPDSFREVAPDSDMPLG-VQEENGIKFEYKILEK 180
            |...||::|:|||:|:.|||||.|.....::.|:....|. ||||.|||:::::.||
Mouse   129 PGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYEK 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhfr	NP_732147.1	DHFR	4..179	CDD:238127	86/180 (48%)
Dhfr	NP_034179.1	DHFR	5..184	CDD:238127	88/182 (48%)