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Protein Alignment Gyc89Db and CYR1

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_012529.3	Gene:	CYR1 / 853452	SGDID:	S000003542	Length:	2026	Species:	Saccharomyces cerevisiae

Alignment Length:	804	Identity:	150/804 - (18%)
Similarity:	260/804 - (32%)	Gaps:	244/804 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 QSFKTHQIYPDKLMPDFAAALSASTGESFDFCMNFFGRCFVR--FFSNFGYDKMIRSTGRYFCDF 96
            :|.:|..::.:.:. ||...:......|.:...|.||...:.  |:.|..|...:..:..:|...
Yeast  1110 KSLRTLDLHSNNIR-DFVDGMENLELTSLNISSNAFGNSSLENSFYHNMSYGSKLSKSLMFFIAA 1173

  Fly    97 LQSIDNIHVQMRFTYPKMKSPSMQLTNMDD------DGAVILYRSGR--TGMS----------KY 143
            ....|:....:...:..:|..::...|..|      :....||.||.  |.:|          |.
Yeast  1174 DNQFDDAMWPLFNCFVNLKVLNLSYNNFSDVSHMKLESITELYLSGNKLTTLSGDTVLKWSSLKT 1238

  Fly   144 LI---GQMTEVAKEFYGLDMTAYVLESQNDICGGTAGPIKLTEGPLTVIVKYRLDFD-------- 197
            |:   .||..:..|...|        ||..:....|..:|..      |..|..|::
Yeast  1239 LMLNSNQMLSLPAELSNL--------SQLSVFDVGANQLKYN------ISNYHYDWNWRNNKELK 1289

  Fly   198 ------NRDYMAKRVNVIAHPSQLKMPSVDLNVFLELFPFTIVLDHDMKITLAGEKIVETWILHN 256
                  ||.:..|  :.|:|.....:.  ||.|..:|....:     |.:||...|:.:
Yeast  1290 YLNFSGNRRFEIK--SFISHDIDADLS--DLTVLPQLKVLGL-----MDVTLNTTKVPD------ 1339

  Fly   257 PGVNPKTFIGSHILERFKCRRPKDTQIQWETILQMRTVLFE-----------------FELIRTG 304
            ..||.:....:.|:...: ....||..|.:.: ..|.|.||                 .:....|
Yeast  1340 ENVNFRLRTTASIINGMR-YGVADTLGQRDYV-SSRDVTFERFRGNDDECLLCLHDSKNQNADYG 1402

  Fly   305 HN-----RAAYD-------------------AALNFDF--------------ENFDEASSLNEAQ 331
            ||     |..||                   .||.|.|              :|..:.::|:.|.
Yeast  1403 HNISRIVRDIYDKILIRQLERYGDETDDNIKTALRFSFLQLNKEINGMLNSVDNGADVANLSYAD 1467

  Fly   332 AMALASA-------KEFSAENAKEEAAAAATSKDEIDPATGQRRHSVGLRS----ILLKGQMFYI 385
            .::.|.:       |:..|.|..:  ..|..||:..|..|..::|....|.    |.:.|.....
Yeast  1468 LLSGACSTVIYIRGKKLFAANLGD--CMAILSKNNGDYQTLTKQHLPTKREEYERIRISGGYVNN 1530

  Fly   386 KDVDSLIFLCSPLIENLDELHGIGLYLNDLNPH-------------GLSRELVMAG---WQHCSK 434
            ..:|.::          |....:|.:  ||.||             .....|::|.   |::...
Yeast  1531 GKLDGVV----------DVSRAVGFF--DLLPHIHASPDISVVTLTKADEMLIVATHKLWEYMDV 1583

  Fly   435 LEIMFEKEEQRSDELEKSLELADSWKRQGDE--------LLYS---------------MIPRPIA 476
            ..:.....|..:|.|..:.||.|.....|..        .||.               |..|...
Yeast  1584 DTVCDIARENSTDPLRAAAELKDHAMAYGCTENITILCLALYENIQQQNRFTLNKNSLMTRRSTF 1648

  Fly   477 E--RMRKSEEHVCQSFEEVSVIFIEVMN---IYDSGSNNIQDAMQ-AVTTLNKVFSALDEEIISP 535
            |  .:|:.:..:......::::|.::.:   :::...|    ||: |:.|.|.:   :..::...
Yeast  1649 EDTTLRRLQPEISPPTGNLAMVFTDIKSSTFLWELFPN----AMRTAIKTHNDI---MRRQLRIY 1706

  Fly   536 FVYKVETVGMVYMAVSGAPDVNPLHAEHACDLALRVMKKVKAHALP------------------- 581
            ..|:|:|.|..:|.....|       .......|.|..|:.....|
Yeast  1707 GGYEVKTEGDAFMVAFPTP-------TSGLTWCLSVQLKLLDAQWPEEITSVQDGCQVTDRNGNI 1764

  Fly   582 ---GVAIRVGINSG-PVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSN--YTAL-KVQ 639
               |:::|:||:.| ||..  :.:...|....|..||.|:|::..:|...|.:|:  |:.. |:.
Yeast  1765 IYQGLSVRMGIHWGCPVPE--LDLVTQRMDYLGPMVNKAARVQGVADGGQIAMSSDFYSEFNKIM 1827

  Fly   640 KVGYKVEARGFVKVKGKGEM-ETY 662
            |...:|       ||||..: |.|
Yeast  1828 KYHERV-------VKGKESLKEVY 1844

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.